Faʻamalieina

Faʻatumu o se suʻega toto e fua ai le gaioiga o ni polotini i le vai vaega o lou toto.

O le faʻamalosia tino o se vaega o toeititi lava 60 porotini o loʻo i le toto toto poʻo luga o luga o nisi sela. O polotini e galue ma lau immune system ma fai se sao e puipuia ai le tino mai faʻamaʻi, ma aveese sela mate ma mea mai fafo. E seasea lava, e ono maua e tagata le le lava o nisi protein faʻatumuina. O nei tagata e ono aafia i ni faʻamaʻi pipisi poʻo ni faʻamaʻi o le autoimmune.

E iva tetele tetele fesoasoani polotini. Ua faʻaigoaina C1 e oʻo i C9. Lenei tusitusiga faʻamatalaina le suʻega e fuaina atoa aofaʻi gaioiga gaioiga.

E manaʻomia se faʻataʻitaʻiga ole toto. Lenei e masani ona faia i se uaua. O le auala e taʻua o le venipuncture.

E leai se sauniuniga faʻapitoa.

A faʻaofi le nila e utu ai le toto, o nisi tagata e lagona sina tiga. O isi e ono lagona naʻo se tuia poʻo se tui. A maeʻa, atonu e i ai ni faʻagatete.

Aofaʻi faʻamalositino gaioiga (CH50, CH100) vaʻai i le aotelega gaioiga o le faʻaopoopoina polokalama. I le tele o tulaga, o isi suʻega e sili ona faʻapitoa mo le masalosalo faʻamaʻi e muamua faia. C3 ma C4 o vaega lagolago e fua tele i taimi uma.

E mafai ona faʻaaoga se suʻesuʻega fesoasoani e mataitu ai tagata e maua i le faʻamaʻi ole autoimmune. E faʻaaogaina foʻi e vaʻai pe o faʻaoga togafitiga mo latou tulaga. Mo se faʻataʻitaʻiga, o tagata e maua i le lupus erythematosus e ono maualalo le maualuga o le vaega o le protein C3 ma le C4.

Faʻalauteleina gaioiga eseese i le tino atoa. Mo se faʻataʻitaʻiga, i tagata e maua i le rheumatoid gugu, o gaioiga faʻaopoopo i le toto atonu e masani pe maualuga atu nai lo le masani ai, ae sili atu maualalo-nai lo-masani i le soʻoga suavai.

Tagata e iai faʻamaʻi toto siama ma faʻateʻia e masani ona maualalo C3 ma vaega ole mea e taʻua ole isi auala. C3 e masani foi ona maualalo i inifula siama ma nisi faʻamaʻi pipisi pei o malaria.

O iʻuga masani mo lenei suʻega o:

• Aofaʻiga toto faʻaopoopo tulaga: 41 i le 90 hemolytic iunite
• C1 tulaga: 14.9 i le 22.1 mg / dL
• C3 tulaga: 88 i le 201 mg / dL
• C4 tulaga: 15 i le 45 mg / dL

Faʻaaliga: mg / dL = milligrams ile deciliter.

Faʻaliga: O tulaga masani o tulaga faʻatulagaina e ono eseese teisi i potu eseese o fale suʻesuʻe. Talanoa i lau soifua maloloina e uiga i le uiga o au faʻapitoa suʻega iʻuga.

O faʻataʻitaʻiga i luga atu o loʻo faʻaalia ai fuataga masani mo iʻuga mo nei suʻega. O nisi potu suesue e faʻaaoga eseese fuataga pe ono suʻesuʻeina faʻataʻitaʻi eseese.

Faʻateleina fesoasoani fesoasoani e mafai ona vaʻaia i le:

• Kanesa
• Nisi faʻamaʻi
• Ulcerative colitis

O le faʻaititia o galuega fesoasoani e mafai ona vaaia i le:

• Cirrhosis
• Glomerulonephritis
• Tupuaga angioedema
• Hepatitis
• Teteʻeina le tipiina o fatugaʻo
• Lupus nephritis
• Paleni meaai
• Systemic lupus erythematosus
• E seasea maua ni mea lelei atoatoa

O faʻafitauli e fesoʻotaʻi ma le tosoina o le toto e laʻititi, ae mafai ona aofia ai:

• Toto tele
• Faaseʻe pe lagona le mumu o le ulu
• Hematoma (toto faʻaputuputu i lalo o le paʻu)
• Faamaʻi (o se laʻititi tulaga lamatia soʻo se taimi le paʻu ua paʻu)

O le "kascade fesoasoani" o se faasologa o tali e faia i le toto. O le cascade faʻagaoioia le faʻatumu protein. O le iʻuga o le osofaʻiga lea e fausia ai pu i le membrane o siama, ma fasiotia ai i latou.

Faʻataʻitaʻiga faʻataʻitaʻi; Faʻatumu polotini

• Tofotofoga toto

Chernecky CC, Berger BJ. C. I le: Chernecky CC, Berger BJ, eds. Suʻesuʻega a le Falesuesue ma Taualumaga o Suʻesuʻega. 6th ed. St Louis, MO: Elsevier Saunders; 2013: 266-432.

Holers VM. Faʻatumuina ma ona taliaina: malamalamaaga fou i faʻamaʻi a tagata. Annu Rev Immunol. 2014; 3: 433-459. PMID: 24499275 www.ncbi.nlm.nih.gov/pubmed/24499275.

Merle NS, Church SE, Fremeaux-Bacchi V, Roumenina LT. Faʻatumuina le vaega vaega I - molemini auala o le faʻagaoioia ma faʻatonutonu. Luma Puipuiga. 2015; 6: 262. PMID: 26082779 www.ncbi.nlm.nih.gov/pubmed/26082779.

Merle NS, Noe R, Halbwachs-Mecarelli L, Fremeaux-Bacchi V, Roumenina LT. Faʻamaea faiga vaega II: matafaioi i le puipuiga. Luma Puipuiga. 2015; 6: 257. PMID: 26074922 www.ncbi.nlm.nih.gov/pubmed/26074922.

Morgan BP, Harris CL. Faʻamalieina, o se faʻamoemoe mo togafitiga i faʻamaʻi mumu ma faʻaleagaina. Nat Rev Fualaʻau Discov. 2015; 14 (2): 857-877. PMID: 26493766 www.ncbi.nlm.nih.gov/pubmed/26493766.