Tusitala: Virginia Floyd
Aso O Foafoaga: 12 Aukuso 2021
Faafouga Aso: 20 Setema 2024
Anonim
PDL1 (Immunotherapy) Suʻega - VailaʻAu
PDL1 (Immunotherapy) Suʻega - VailaʻAu

Anotusi

Ole a le suʻega ole PDL1?

O lenei suʻega e fua ai le aofaʻi o PDL1 i sela kanesa. PDL1 o se polotini e fesoasoani e taofia sela puipuia mai le osofaʻia o le le mataʻutia sela i le tino. O le mea masani, o le immune system e tau ai vailaʻau mai fafo pei o siama ma siama, ae le o au lava sela maloloina. O isi sela kanesa e maualuga le aofaʻi o PDL1. E faʻatagaina ai sela o le kanesa ona "togafiti" le puipuiga o le tino, ma 'aloʻese mai le osofaʻia o ni vailaʻau mataʻutia.

A faʻapea o lou kanesa sela e iai le maualuga o PDL1, oe ono faʻamanuiaina mai se togafitiga ua taʻua o le immunotherapy. Immunotherapy o se togafitiga e faʻamalosia ai lou tino puipuia e fesoasoani ia iloa ma tau ai sela kanesa. Immunotherapy ua faʻaalia e sili ona lelei i le togafitia o nisi ituaiga o kanesa. E faʻapea foi ona i ai ni faʻafitauli laiti nai lo isi togafitiga kanesa.

Isi igoa: faʻapolokalameina le maliu-ligand 1, PD-LI, PDL-1 e le immunohistochemistry (IHC)

O le a le mea e faʻaaoga ai?

PDL1 suʻega e faʻaogaina e suʻe ai pe o iai sau kanesa e ono aoga mai le faʻamalosi tino.


Aisea ou te manaʻomia ai se suʻega PDL1?

Oe ono manaʻomia PDL1 suʻega pe a fai oe ua faʻamaonia i se tasi o nei kanesa:

  • Le-laiti sela sela kanesa
  • Melanoma
  • Hodgkin lymphoma
  • Kanesa o le tagāmimi
  • Kanesa o fatugaʻo
  • Kanesa o le susu

Maualuga tulaga o PDL1 e masani ona maua i nei, faʻapea foi ma isi ituaiga o kanesa. O kanesa e maualuga le maualuga o le PDL1 e masani ona togafitia lelei i tui puipui.

Ole a le mea e tupu ile taimi ole suʻega ole PDL1?

Ole tele ole suʻega ole PDL1 e faia ile faiga e taʻua ole biopsy. E tolu ituaiga autu ole faʻasologa o le biopsy:

  • Biopsy moomoo manaʻomia lelei lea e faʻaaoga ai se nila manifinifi e aveʻese ai se faʻataʻitaʻiga o sela poʻo suavai
  • Biopsy nila nila, lea e faʻaaoga ai se nila tele e aveʻese ai se faʻataʻitaʻiga
  • Biopsy taotoga, lea aveese se faʻataʻitaʻiga i se laʻititi, outpatient gaioiga

Manatu lelei moʻa ma biopsies autu nila masani ona aofia ai laʻasaga nei:


  • O le a e taoto i ou tafatafa pe nofo i luga o le laulau suʻega.
  • O le tausi soifua maloloina o le a faʻamamaina le nofoaga o le biopsy ma tuiina i se vailaʻau faʻapitoa ina ia oe o le a le lagonaina se tiga i le taimi o le gaioiga.
  • O le taimi lava e leai se mea o le eria, o le a tuʻuina atu e le kamupani tuʻuina atu a lelei nila manaʻomia poʻo nila biopsy autu i le biopsy nofoaga ma aveʻese se faʻataʻitaʻiga o aano o le tino poʻo suavai.
  • Atonu e te lagonaina sina faʻamalosiʻau pe a toʻesea le faʻataʻitaʻi.
  • O le a faʻamalosia le faʻamalosiina i le nofoaga o le biopsy seʻia maeʻa le tafetoto.
  • O lau tautua o le a tuʻuina se mea faʻamoe i le nofoaga o le biopsy.

I se taotoga biopsy, o le fomai tipitipi o le a faia sina tamaʻi tipi i lou paʻu e aveʻese uma poʻo se vaega o le fatafata susu. O se taotoga biopsy e faia i nisi taimi pe a fai e le mafai ona aʻapa le lump i se nila biopsy. O taotoga faʻapitoa e masani ona aofia ai laʻasaga nei.

  • O le a e taʻoto i luga o le laulau faʻagaioia. E mafai ona tuʻuina se IV (laina faʻatumu) i lou lima poʻo lou lima.
  • Atonu e avatua ia te oe vailaʻau, e taʻu ole vailaʻau, e fesoasoani e te malolo ai.
  • Oe o le a tuʻuina atu i le lotoifale poʻo le lautele vai faagase faʻapea e te le o lagonaina tiga i le taimi o le gaioiga.
    • Mo vai faagase i le lotoifale, o le a tuiina e le tausi soifua maloloina le nofoaga o le biopsy ma vailaʻau e faʻanofo ai le eria.
    • Mo lautele vai faagase, o se faʻapitoa valaʻauina se vailaʻau faʻapitoa o le a avatua ia te oe vailaʻau o lea o le a e matapogia ai i le taimi o le gaioiga.
  • O le taimi lava e leai se aoga o le vaega o le biopsy pe e te leʻo iloaina foi, o le a faia e le fomai tipitipi sina tipi i totonu o le fatafata ma aveʻese vaega poʻo se atoa o se paluga. E mafai foʻi ona aveʻese isi mea i autafa o le pu.
  • O le tipi i lou paʻu o le a tapunia ma suʻi poʻo ni fasi pepa faʻapipiʻi.

E i ai ituaiga eseese o biopsies. Ole ituaiga biopsy e te maua e faʻamoemoe ile nofoaga ma le tele o lou tumo.


Mata e tatau ona ou faia se mea e sauniuni ai mo le suʻega?

E te le manaʻomia ni sauniuniga faʻapitoa pe a fai o loʻo e mauaina se vai faagase i le lotoifale (faʻamamaina o le nofoaga o le biopsy). Afai o loʻo e mauaina le faʻateʻa lautele, e ono manaʻomia ona e anapogi (aua le 'ai pe inu) mo ni nai itula ae e te leʻi faia se taʻotoga. O lau fomai tipitipi o le a avatua ia te oe nisi faʻatonuga faʻapitoa. Faʻapea foi, afai o loʻo e mauaina se vailaʻau faʻasoesa poʻo le lautele, ia mautinoa e teuteuina seisi e aveina oe i le fale. Atonu e te maʻa ma le mautonu pe a maeʻa ona e ala mai i le faiga.

E i ai ni lamatiaga i le suʻega?

E i ai sina manuʻa poʻo se toto i le nofoaga na fausia ai le biopsy. O nisi taimi e afaina ai le 'upega tafaʻilagi. Afai e tupu lena mea, o le a togafitia oe ma vailaʻau oona. O se taotoga biopsy e ono mafua ai nisi tiga ma le le mautonu. Atonu e fautuaina e lau fomaʻi ni talavai e fesoasoani ia te oe ia maua se lagona lelei.

O le a le uiga o faʻaiuga?

Afai o au faʻaiuga faʻaalia lou sela sela maualuga maualuga o PDL1, oe ono amata i luga o tui puipuia. A faʻapea e le o faʻaalia mai i au iuga le maualuga o le PDL1, e ono le aoga ia oe. Ae ono faʻamanuiaina oe ile isi ituaiga togafitiga o le kanesa. A iai ni au fesili e uiga i au iʻuga, talanoa i lau fomaʻi.

Aʻoaʻo atili e uiga i suʻesuʻega falesuesue, vaitau o faʻasino, ma malamalamaaga i iʻuga

E iai se isi mea e tatau ona ou iloa e uiga ile suʻega PDL1?

Immunotherapy e le galue mo tagata uma, tusa lava pe i ai ni au tuma ma maualuga maualuga o le PDL1. O sela o le kanesa e faigata ma e le masani ai. O loʻo aʻoaʻoina pea e le au tausi soifua ma tagata suʻesuʻe ia tui puipuia ma faʻafefea ona valoʻia poʻo ai e sili ona faʻamanuiaina i lenei togafitiga.

Faʻamatalaga

  1. Allina Soifua Maloloina [Initaneti]. Minneapolis: Soifua Maloloina Allina; c2018. Immunotherapy mo kanesa; [taʻua 2018 Aug 14]; [pe tusa ma le 3 pupuni] Avanoa mai: https://wellness.allinahealth.org/library/content/60/903
  2. American Cancer Society [Initaneti]. Atlanta: American Cancer Society Inc. c2018. Vaʻaia siaki siaki siaki e togafitia kanesa; [toe faafou 2017 Me 1; taʻua 2018 Aug 14]; [tusa o le 4 pupuni] Avanoa mai: https://www.cancer.org/treatment/treatments-and-side-effects/treatment-types/immunotherapy/immune-checkpoint-inhibitors.html
  3. American Cancer Society [Initaneti]. Atlanta: American Cancer Society Inc. c2018. O le a le faʻataʻitaʻiga o le Kanesa? [faafou 2016 Jun 6; taʻua 2018 Aug 14]; [tusa o le 4 pupuni] Avanoa mai: https://www.cancer.org/treatment/treatments-and-side-effects/treatment-types/targeted-therapy/what-is.html
  4. American Cancer Society [Initaneti]. Atlanta: American Cancer Society Inc. c2018. Ole a fou ile suʻesuʻega ole kanesa ole kanesa?; [faafou 2017 Oketopa 31; taʻua 2018 Aug 14]; [tusa o le 4 pupuni] Avanoa mai: https://www.cancer.org/treatment/treatments-and-side-effects/treatment-types/immunotherapy/whats-new-in-immunotherapy-research.html
  5. Cancer.Net [Initaneti]. Alexandria (VA): American Society of Clinical Oncology; c2005-–2018. 9 Mea e Iloa e uiga i Immunotherapy ma Kanesa kanesa; 2016 Nov 8 [taʻua 2018 Aug 14]; [pe tusa ma le 3 pupuni] Avanoa mai: https://www.cancer.net/blog/2016-11/9-things- know-about-immunotherapy-and-lung-cancer
  6. Dana-Farber Cancer Institute [Initaneti]. Boston: Dana-Farber Cancer Institute; c2018. O le a le PDL-1 Suʻega?; 2017 Me 22 [faʻafouina 2017 Jun 23; taʻua 2018 Aug 14]; [pe tusa ma le 3 pupuni] Avanoa mai: https://blog.dana-farber.org/insight/2017/05/what-is-a-pd-l1-test
  7. Integrated Oncology [Initaneti]. Laboratory Corporation o Amerika, c2018. PDL1-1 e IHC, Opdivo; [taʻua 2018 Aug 14]; [pe tusa ma le 3 pupuni] Avanoa mai: https://www.integratedoncology.com/test-menu/pd-l1-by-ihc-opdivo%C2 %AE/cec2cfcc-c365-4e90-8b79-3722568d5700
  8. Lab Tofotofoga lugalaina [Initaneti]. Washington D.C .: American Association mo Vailaʻau Togafitiga; c2001–2018. Suʻesuʻega faʻafuaseʻi mo le faʻataʻitaʻia o le kanesa; [faafou 2018 Jun 18; taʻua 2018 Aug 14]; [pe a ma le 2 pupuni] Avanoa mai: https://labtestsonline.org/tests/genetic-tests-targeted-cancer-therapy
  9. Mayo Clinic: Mayo Medical Laboratories [Initaneti]. Mayo Faʻavae mo Aʻoga Faʻafomaʻi ma Suesuega; c1995–2018. ID faʻataʻitaʻi: PDL1: Polokalame Oti-Ligand 1 (PD-L1) (SP263), Semi-Quantitative Immunohistochemistry, Tusi Lesona: Fomaʻi ma Faamatala; [taʻua 2018 Aug 14]; [tusa o le 4 pupuni] Avanoa mai: https://www.mayomedicallaboratories.com/test-catalog/Clinical+and+Interpretive/71468
  10. MD Anderson Cancer Center [Initaneti]. O le Iunivesite o Texas MD Anderson Kanesa Tutotonu; c2018. O lenei mauaina ono faʻateleina aoga o tui puipuia; 2016 Sep 7 [taʻua 2018 Aug 14]; [pe tusa ma le 3 pupuni] Avanoa mai: https://www.mdanderson.org/publications/cancer-frontline/2016/09/discovery-may-increase-immunotherapy-effectiveness.html
  11. National Cancer Institute [Initaneti]. Bethesda (MD): U.S. Matagaluega o le Soifua Maloloina ma Tagata Auaunaga; NCI Lomifefiloi o Kanesa Tuutuuga: tui puipuia; [taʻua 2018 Aug 14]; [pe tusa ma le 3 pupuni] Avanoa mai: https://www.cancer.gov/publications/dictionaries/cancer-terms/def/immunotherap
  12. National Cancer Institute [Initaneti]. Bethesda (MD): U.S. Matagaluega o le Soifua Maloloina ma Tagata Auaunaga; Tumua Faʻailoga; [taʻua 2018 Aug 14]; [tusa o le 4 pupuni] Avanoa mai: https://www.cancer.gov/about-cancer/diagnosis-staging/diagnosis/tumor-markers-fact-sheet
  13. Le Sydney Kimmel Comprehensive Cancer Center [Initaneti]. Baltimore: O le Iunivesite o Johns Hopkins; Mataupu Fatafata: Faʻamalosi tino le puipuia e puipuia ai mo le kanesa o le susu; [taʻua 2018 Aug 14]; [pe tusa ma le 3 pupuni] Avanoa mai: https://www.hopkinsmedisin.org/news/publications/breast_matters/files/sebindoc/a/p/ca4831b326e7b9ff7ac4b8f6e0cea8ba.pdf
  14. UW Soifua Maloloina [Initaneti]. Madison (WI): Iunivesite o Wisconsin Falemai ma Falemai Pulega; c2018. Faʻamatalaga o le Soifua Maloloina: Immune System; [faafou 2017 Oketopa 9; taʻua 2018 Aug 14]; [pe tusa ma le 3 pupuni] Avanoa mai: https://www.uwhealth.org/health/topic/ConditionCenter/Immune%20System/center1024.html
  15. UW Soifua Maloloina [Initaneti]. Madison (WI): Iunivesite o Wisconsin Falemai ma Falemai Pulega; c2018. Tala Fou ma Mea na Tutupu: Aʻoaʻoina le Tino Puipuiga e Tau ai I le Kanesa; [faafou 2017 Aukuso 7; taʻua 2018 Aug 14]; [pe tusa ma le 3 pupuni] Avanoa mai: https://www.uwhealth.org/news/the-immune-system-goes-to-school-to-learn-how-to-fight-cancer/51234

O faʻamatalaga i luga o lenei 'upega tafaʻilagi e le tatau ona faʻaaogaina e fai ma sui o fomaʻi faʻapitoa togafitiga poʻo fautuaga. Faʻafesoʻotaʻi le au tausi soifua pe a iai ni au fesili e uiga i lou soifua maloloina.

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