Fibrates

Fibrates o vailaʻau faʻatonuina e fesoasoani i lalo maualalo maualuga triglyceride tulaga. Triglycerides o se ituaiga gaʻo i lou toto. Fibrates mafai foi ona fesoasoani e faʻateleina lau HDL (lelei) cholesterol.

Maualuga triglycerides faʻatasi ai ma le maualalo o le HDL cholesterol faʻateleina le ono aʻafia o faʻamaʻi fatu ma le afaina.

O le tuʻuina i lalo ole kolisi ma triglycerides e mafai ona fesoasoani e puipuia oe mai faʻamaʻi fatu, fatu fatu, ma papala.

O Statins e manatu o ni vailaʻau e sili ona lelei e faʻaaoga mo tagata e manaʻomia vailaʻau e tuʻu ai i lalo le latou kolisi.

Nisi fibrates ono faʻatonuina faʻatasi ma statins e fesoasoani tuʻu i lalo kolesterol. Peitai, o nisi suʻesuʻega faʻaalia ai o le faʻaaogaina o nisi fibrates faʻatasi ai ma statins atonu e le fesoasoani e faʻaititia ai le aʻafiaga o le fatu faʻamaʻi poʻo le stroke sili atu nai lo le faʻaaogaina o statins naʻo ia.

Fibrates mafai foi ona faʻaaogaina e fesoasoani ai i lalo maualalo maualuga triglycerides i tagata ono afaina mo pancreatitis.

Fibrates e faatonuina i tagata matutua.

Ave lau vailaʻau pei ona faatonuina.E masani ona faia 1 taimi ile aso. Aua le taofia le inuina o au vailaʻau e aunoa ma le talanoa muamua ma lau fomaʻi.

O le vailaʻau sau i totonu suavai-tumu kapisi poʻo fomu fomu. Aua le tatalaina atigipusa, lamulamu, pe tuʻimomomo papa i luma o inu.

Faitau faʻatonuga i lau igoa faʻafomaʻi. Nisi ituaiga e tatau ona ave ma meaai. O isi e ono aveina ma, pe leai ni meaai.

Teu uma au vailaʻau i se nofoaga malulu ma mago.

Mulimuli i se soifua maloloina soifua maloloina ao avea fibrates. E aofia ai le 'ai sina laʻititi i lau taumafataga. Isi auala e mafai ona e fesoasoani ai i lou fatu aofia ai:

• Faʻamalositino masani
• Puleaina o le popole
• Tuu le ulaula

Ae e te leʻi amata amataina fibrates, taʻu i lau tautua peʻa e:

• Ua maʻitaga, fuafua e maʻitaga, pe o susu susu. E le tatau i tina tausimaʻi ona inu lenei vailaʻau.
• I ai ni mea e aliali mai
• O inuina isi vailaʻau
• Fuafua e fai sau taotoga poʻo nifo galuega
• Maʻi suka

Afai e i ai lou ate, gallbladder, poʻo fatugaʻi tulaga, oe le tatau ona ave fibrates.

Taʻu i lau kamupani e uiga i au vailaʻau uma, vailaʻau, vitamini, ma fualaʻau. Nisi vailaʻau ono fesoʻotaʻi ma fibrates. Ia mautinoa e taʻu i lau tautua ae e leʻi inuina ni au vailaʻau fou.

O taimi uma suʻega toto o le a fesoasoani ia te oe ma lau tautua:

• Vaʻai pe faʻafefea ona ola lelei vailaʻau
• Mataʻituina ni aʻafiaga, pei o le ate

Aafiaga ono mafai ono aofia ai:

• Tigā ulu
• Paneta
• Manava tata
• Faanenefu
• Manava tiga

Valaʻau lau tautua pe a e matauina:

• Tiga o le manava
• Tiga o maso poʻo le agavaivai
• Vaivaiga
• Lanu samasama o le paʻu (jaundice)
• Paʻu mageso
• Isi faʻailoga fou

Sooupu Antilipemic; Fenofibrate (Antara, Fenoglide, Lipofen, Tricor, ma Triglide); Gemfibrozil (Lopid); Fenofibric acid (Trilipix); Hyperlipidemia - fibrates; Faʻaʻaʻa o alatoto - fibrates; Cholesterol - fibrates; Hypercholesterolemia - fibrates; Dyslipidemia - fibrates

'Upega Tafaʻilagi a le American Heart Association. Cholesterol vailaʻau. www.heart.org/en/health-topics/cholesterol/prevention-and-treatment-of-high-cholesterol-hyperlipidemia/cholesterol-medications. Faʻafouina Novema 10, 2018. Avanoa ia Mati 4, 2020.

Genest J, Libby P. Lipoprotein faʻafitauli ma faʻamaʻi fatu. I: Zipes DP, Libby P, Bonow RO, Mann DL, Tomaselli GF, Braunwald E, eds. Braunwald's Heart Disease: O Se Tusitusiga o Faʻafomaʻi Cardiovascular. 11th lomiga. Filatelefia, PA: Elsevier; 2019: chap 48.

Grundy SM, Stone NJ, Bailey AL, et al. 2018 AHA / ACC / AACVPR / AAPA / ABC / ACPM / ADA / AGS / APhA / ASPC / NLA / PCNA taiala i luga o le puleaina o le toto toto: o se lipoti a le American College of Cardiology / American Heart Association Task Force on Clinical Practice Guide. . J Am Coll Cardiol. 2019; 73 (24): e285 – e350. PMID: 30423393 pubmed.ncbi.nlm.nih.gov/30423393/.

Jones PH, Brinto EA. Fibrates. I: Ballantyne CM, ed. Fomaʻi Lipidology: O se Soa i le Braunwald's Heart Disease. 2nd ed. Filatelefaia, PA: Elsevier Saunders; 2015: mata 25.

Uepisaite a le US Food and Drug Administration. Fesoʻotaʻiga mo le saogalemu o fualaʻau a le FDA: toe iloilo le faʻafouga o le trilipix (fenofibric acid) ma le ACCORD lipid trial. www.fda.gov/drugs/drug-safety-and-availability/fda-drug-safety-communicationreview-update-trilipix-fenofibric-acid-and-accord-lipid-trial. Faʻafouina Fepuari 13, 2018. Avanoa ia Mati 4, 2020.

• Vailaau Cholesterol
• Triglycerides