Quantitative Bence-Jones porotini suʻega

O lenei suʻega e fua ai le maualuga o polotini e le masani ai e taʻua o le Bence-Jones proteins i le miaga.

E manaʻomia se faʻataʻitaʻi mamā mama. O le mama-puʻe metotia o loʻo faʻaaogaina e puipuia ai siama mai le pene poʻo le fafine fafine mai le mauaina i totonu o se faʻataʻitaʻi vai. Ina ia aoina lau miaga, e mafai ona avatu ia te oe e le tausi soifua maloloina se pusa faʻapitoa e faʻamamaina-o loʻo i ai se fofo faʻamama ma solo solo. Usitaʻi i faʻatonuga saʻo ina ia saʻo faʻaiuga.

Ua lafo le faʻataʻitaʻiga i le fale suesue. O iina, o se tasi o le tele o metotia o loʻo faʻaaogaina e iloa ai protein Bence-Jones. Tasi le metotia, ua faʻaigoaina ole immunoelectrophoresis, e pito sili ona saʻo.

O le suʻega e aofia ai na o le masani urination, ma e leai se le mautonu.

Bence-Jones proteins o se vaega o masani ona faʻamalosi tino e taʻua o filifili mama. O nei polotini e le masani i le miaga. O isi taimi, pe a fai o lou tino e tele naua antodies, o le maualuga o filifili malamalama faʻalauteleina foi. Bence-Jones proteins e laʻititi lava e mafai ona faʻamamaina e fatugaʻo. Ona sosolo atu lea o polotini i le miaga.

E ono okaina e lau tautua lenei suʻega:

• E faʻamaonia ai tulaga ia e oʻo atu ai ile polotini ile miaga
• Afai e tele lau polotini i lau miaga
• A iai ni faʻailoga o le kanesa ole toto e taʻua o le myeloma e tele

O se faʻaiuga masani o lona uiga e leai ni polotini Bence-Jones e maua i lau miaga.

E seasea maua i le miaga ia protein Bence-Jones. Afai o latou, e masani ona fesoʻotaʻi ma tele myeloma.

O se faʻaletonu iʻuga mafai foi ona mafua mai i:

• O se le masani ai le fausiaina o polotini i aano ma totoga (amyloidosis)
• O le kanesa ole toto e taʻua ole lepisemia lymphocytic faaumiumi
• Kanesa ole Lymph system (lymphoma)
• Fausiaina i le toto o se polotini taʻua M-protein (monoclonal gammopathy o le iloaina le taua; MGUS)
• Faʻafitauli ogaoga fatugaʻo

E leai ni lamatiaga i lenei suʻega.

Filifili mama Immunoglobulin - miaga; Mimi Bence-Jones polotini

• Lalolagi urinary faiga

Chernecky CC, Berger BJ. Protein electrophoresis - miaga. I le: Chernecky CC, Berger BJ, eds. Suʻesuʻega a le Falesuesue ma Taualumaga o Suʻesuʻega. 6th ed. St Louis, MO: Elsevier Saunders; 2013: 920-922.

Riley RS, McPherson RA. Suʻega masani ole miaga. I totonu: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management e le Laboratory Metotia. 23rd ed. St Louis, MO: Elsevier; 2017: mata 28.

Rajkumar SV, Dispenzieri A. Tele myeloma ma faʻafitauli fesoʻotaʻi. I: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, eds. Abeloff's Clinical Oncology. 6th ed. Filatelefia, PA: Elsevier; 2020: chap 101.