Kanesa ole ate - hepatocellular carcinoma

Hepatocellular carcinoma ole kanesa e amata ile ate.

Hepatocellular kanesa kanesa mo tele kanesa ate. O lenei ituaiga kanesa e tupu soo i alii nai lo fafine. E masani ona faʻamaonia i tagata ua 50 tausaga pe sili atu.

Hepatocellular carcinoma e le tutusa ma le kanesa o le ate metastatic, lea e amata i seisi totoga (pei o le fatafata poʻo le kolone) ma salalau atu i le ate.

I le tele o tulaga, o le mafuaʻaga o le kanesa o le ate o le umi-taimi faʻaletonu ma maʻila o le ate (cirrhosis). Cirrhosis ono mafua mai i:

• Faʻasuaʻava i le 'ava malosi
• O faʻamaʻi o le ate o le ate
• Hepatitis B poʻo le siama hepatitis C siama
• Fula o le ate o se taimi umi (tumau)
• Uʻamea tele i le tino (hemochromatosis)

O tagata e maua i le hepatitis B poʻo le C e tele le avanoa i le kanesa o le ate, tusa pe latou te le maua i le cirrhosis.

Faʻailoga o le kanesa ole ate e mafai ona aofia ai mea nei:

• Manava manava po o le agavaivai, aemaise lava i le pito i luga taumatau vaega
• Faigofie gagala pe puna toto
• Faʻateleina manava (ascites)
• Paʻu samasama po o mata (jaundice)
• Le mafaamatalaina mamafa leiloa

O le a faʻatautaia e le fomaʻi le soifua maloloina se suʻega o le tino ma fesili e uiga i ou faʻailoga. O le suʻega faʻaletino e ono faʻaalia ai se faʻalauteleina, mu malu poʻo isi faʻailoga o le cirrhosis.

Afai e masalomia e le 'auʻaunaga le kanesa ole ate, o suʻega e ono okaina e aofia ai:

• Suʻega CT scan
• Suʻega MRI scan
• Laʻititi ultrasound
• Biopsy o le ate
• Suʻega gaioiga ole ate
• Serum alpha fetoprotein

O nisi tagata e tele le avanoa e maua ai ile kanesa ole ate e ono maua i taimi uma suʻesuʻega toto ma ultrasounds e iloa ai pe o tupu ni patu.

Ina ia faʻamaonia lelei le kanesa o le hepatocellular, e tatau ona faia se suesuega o le tumo.

Togafitiga faʻalagolago i le alualu i luma o le kanesa o.

E mafai ona fai taotoga pe a fai e leʻi sosolo le tumo. Aʻo leʻi faia se taotoga, e mafai ona togafitia le tuma ile chemotherapy e faʻaititia ai lona tele. E faia lea i le tuʻu saʻo atu o vailaʻau i le ate ma le paipa (catheter) poʻo le tuʻuina i totonu (e le IV).

E mafai foi ona fesoasoani togafitiga i le vaega ole kanesa.

Faʻamutaina o seisi auala e mafai ona faʻaaogaina. Faʻaola o lona uiga faʻaumatia. Ituaiga o faʻauʻuina aofia ai le faʻaaogaina:

• Leitio galu poʻo niu faʻaitu
• Ethanol (o se ava malosi) poʻo acetic acid (vineka)
• Malulu tele (cryoablasi)

E mafai ona fautuaina se tui ile ate.

Afai e le mafai ona aveʻesea le kanesa pe ua sosolo i fafo o le ate, e masani ona leai se avanoa mo se faʻamalologa mo se taimi umi. Togafitiga nai lo taulaʻi atu i le faʻaleleia ma le faʻalauteleina o le ola o le tagata. Togafitiga i lenei tulaga ono faʻaaoga togafitiga faʻatulagaina ma vailaʻau e mafai ona avea o ni fualaʻau. E mafai foi ona faʻaaogaina ni vailaʻau fou mo le tui puipuia.

Oe mafai ona faʻafaigofieina le popolevale o maʻi i le auai i le kulupu lagolago vaega. O le fefaʻasoaaʻi ma isi e masani ona maua ni faʻafitauli ma faʻafitauli e mafai ona fesoasoani ia te oe e te le lagona ai le tuua toʻatasi.

Afai e le mafai ona togafitia atoatoa le kanesa, o le faʻamaʻi e masani ona afaina. Ae o le ola e mafai ona fesuisuiaʻi, fuafua i le alualu i luma o le kanesa o pe a faʻamaonia ma pe o le a le manuia o togafitiga.

Valaʻau lau tautua pe a fai e te tupu pea le tiga o le manava, aemaise pe a fai o loʻo iai sau tala faʻamaʻi o le ate.

Fuafuaga puipuia e aofia ai:

• Puipuia ma togafitia viral hepatitis ono fesoasoani faʻaititia lou lamatiaga. Tamaititi tui faasaga i le hepatitis B ono faʻaititia le ono maua o le ate kanesa i le lumanaʻi.
• Aua le inu tele i le 'ava malosi.
• Tagata e iai ituaiga o hemochromatosis (uʻamea tele) e manaʻomia le siakiina mo le kanesa ole ate.
• Tagata e maua ile hepatitis B poʻo C ole cirrhosis atonu e fautuaina mo le siaki ole kanesa ole ate.

Tasi sela o le ate sela muamua; Tumua - ate; Kanesa - ate; Hepatoma

• Polokalama Digestive
• Biopsy o le ate
• Kanesa Hepatocellular - CT scan

Abou-Alfa GK, Jarnagin W, Dika IE, et al. Kanesa o le ate ma le gaʻo. I: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, eds. Abeloff's Clinical Oncology. 6th ed. Filatelefia, PA: Elsevier; 2020: chap 77.

Di Bisceglie AM, Befeler AS. Hepatic tuma ma cista. I totonu: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger ma Fordtran's Gastrointestinal ma le Maʻi ole: Pathophysiology / Diagnosis / Pulega. 10 ed. Filatelefaia, PA: Elsevier Saunders; 2016: mata 96.

'Upega Tafaʻilagi a le National Cancer Institute. Togafitiga muamua o le kanesa o le ate (PDQ) - soifua maloloina polofesa. www.cancer.gov/types/liver/hp/adult-liver-treatment-pdq. Faʻafouina Mati 24, 2019. Avanoa i Aukuso 27, 2019.

'Upega Tafaʻilagi National Comprehensive Cancer Network. NCCN falemaʻi faʻataʻitaʻiina faʻatonuga i oncology: kanesa hepatobiliary. Faʻamatalaga 3.2019. www.nccn.org/professionals/physician_gls/pdf/hepatobiliary.pdf. Faʻafou Aukuso 1, 2019. Avanoa Aukuso 27, 2019.