Hemolytic-uremic faʻamaʻi

Shiga-pei oona faʻatupuina E coli hemolytic-uremia syndrome (STEC-HUS) o se faʻamaʻi e masani ona tupu pe a o se siama i le digestive system maua ai vailaʻau oona.O nei vailaʻau faʻaleagaina mumu toto sela ma mafua ai manuʻa manuʻa.

Hemolytic-uremia syndrome (HUS) masani ona tupu pe a maeʻa se gastrointestinal siama ma E coli siama (Escherichia coli O157: H7). Peitai, o le tulaga ua fesoʻotaʻi foʻi ma isi gastrointestinal faʻamaʻi, e aofia ai shigella ma salmonella. Ua fesoʻotaʻi foʻi ma faʻamaʻi nongastrointestinal.

O IA e masani ai tamaiti. O le sili ona taatele mafuaʻaga ogaoga fatugaʻo toilalo i tamaiti. E tele faʻamaʻi tetele na faʻafesoʻotaʻi i aano o manufasi o hamburger e leʻi vela E coli.

E coli mafai ona faʻasalalau e ala i:

• Faʻafesoʻotaʻi mai le tasi tagata i le isi
• Faʻaumaina le le kukaina o meaʻai, pei o susu oloa poʻo povi

STEC-HUS e le tatau ona fenumiai ma atypical HUS (aHUS) e le o fesoʻotaʻiga ma fesoʻotaʻiga. E tali tutusa ma le isi faʻamaʻi e taʻua o le thrombotic thrombocytopenic purpura (TTP).

E masani ona amata le STEC-HUS ile puaʻi ma le manava tata, atonu e toto. I totonu o le vaiaso, e ono vaivai ma itaita le tagata. Tagata e maua i lenei maʻi ono urination laʻititi nai lo masani. E pe toeitiiti uma le galuega mimi.

O le faʻatamaia o le toto mumu e mafua ai faʻailoga o le anemia.

Vave auga:

• Toto i totonu o faʻataʻavalega
• Ita
• Fiva
• Faʻanoanoa
• Faanoi ma manava tatā
• Vaivaiga

Faʻailoga mulimuli ane:

• Manuʻa
• Faʻaitiitia le malamalama
• Galue mimi maualalo
• Leai se suavai maua
• Pallor
• Faoa faamalosi - seasea
• Paʻu o le paʻu e pei o ni lanu mumu mananaia (petechiae)

E faʻataʻitaʻi e le tausi soifua le suʻega o le tino. Atonu e faʻaalia lenei:

• Fula pe faʻafuaseʻi fulafula
• Ua suia suiga o le tino popole

O faʻataʻitaʻiga ile fale suʻesuʻe o le a faʻaalia ai faʻailoga o le hemolytic anemia ma le ogaoga o le fatu. O suʻega e mafai ona aofia ai:

• Suʻega ole faʻaputuga ole toto (PT ma le PTT)
• E mafai ona faʻaalia i le vaega o metabolic auiliili le maualuga o le BUN ma le foafoa
• Ole toto atoa (CBC) e ono faʻaalia ai le faʻatupulaia o le paepae toto ma paʻu le toto mumu toto
• Platelet count e masani ona faʻaititia
• Urinalysis ono faʻaalia le toto ma porotini i le miaga
• E mafai ona faʻaalia i le suʻega le polotini o le mimi le aofaʻi o polotini i le vai

Isi suʻega:

• Ole aganuu ole nofoa e ono lelei mo se ituaiga ituaiga E coli siama poʻo isi siama
• Kolone tetele
• Biopsy o fatugaʻo (i ni mea e seasea tupu)

Togafitiga ono aofia ai:

• Dialysis
• Vailaau, pei o le vailaʻau
• Faʻatonutonuina o vai ma electrolytes
• Tuiina o sela mumu mumu ma lapisi

O lenei o se maʻi tuga i tamaiti uma ma tagata matutua, ma e mafai ona mafua ai le oti. Faatasi ai ma togafitiga talafeagai, sili atu ma le afa o tagata o le a toe maloloina. O le iʻuga e sili atu i tamaiti nai lo tagata matutua.

Faʻafitauli e ono aofia ai:

• Faʻafitauli ole toto
• Hemolytic anemia
• Le manuia fatugaʻo
• Toto maualuga e tau atu i le faoa faamalosi, itaitagofie, ma isi faafitauli o neula
• Tele tamaʻi lapisi (thrombocytopenia)
• Uremia

Valaʻau lau tautua pe a fai e te maua ni faʻailoga o le HUS. Faʻalavelave faʻafuaseʻi e aofia ai:

• Toto i le faʻataulaga
• Leai se urination
• Faʻaititia mataala (mataala)

Valaʻau lau tautua pe a fai na e maua se faʻasologa o le HUS ma ua faʻaititia lau suavai pe, pe ua e atiaʻe isi faʻailoga fou.

Oe mafai ona puipuia le iloa mafuaʻaga, E coli, e ala i le kukaina lelei o hamburger ma isi aano. E tatau foi ona e alo ese mai le faʻafesoʻotaʻiga o le vai le mama ma mulimulitaʻi i metotia tatau o le mulumulima.

FANUA; STEC-HUS; Hemolytic-uremic faʻamaʻi

• Lalolagi urinary faiga

Alexander T, Licht C, Smoyer WE, Rosenblum ND. Faamai o le fatugaʻo ma le pito i luga urinary tamaititi i tamaiti. I: Yu ASL, Chertow GM, Luyckx VA, Marsden PA, Skorecki K, Taal MW, eds. Brenner ma Rector's Le Fatugaʻo. 11th lomiga. Filatelefia, PA: Elsevier; 2020: mata: 72.

Mele C, Noris M, Remuzzi G. Hemolytic uremic syndrome. I: Ronco C, Bellomo R, Kellum JA, Ricci Z, eds. Faʻataʻiga Faʻataʻiga Nephrology. 3rd ed. Filatelefia, PA: Elsevier; 2019: chap 50.

Schneidewend R, Epperla N, Friedman KD. Thrombotic thrombositopenic purpura ma le hemolytic uremic syndromes. I: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Faavae Autu ma Faʻataʻitaʻiga. 7th ed. Filatelefia, PA: Elsevier; 2018: mata 134.