Leukemia myelogenous faaumiumi (CML)

Leukemia masani ole myelogenous leukemia (CML) o le kanesa e amata i totonu o ponaivi ponaivi. O le mea vaivai lea i le ogatotonu o ponaivi e fesoasoani e fausia uma sela o le toto.

CML mafua ai le le faʻatonutonu tuputupu aʻe o le matua ma sela matua e faia ai se ituaiga o papaʻe sela toto taʻua o myeloid sela. O sela mamaʻi e faʻaputuputu i le ponaivi ponaivi ma le toto.

Mafuaʻaga o le CML e fesoʻotaʻi ma se le lelei chromosome taʻua o le Philadelphia chromosome.

O le faʻaaliga malamalama e mafai ona faʻateleina ai le aʻafia o le CML. O le faʻamalamalamaina o le malamalama e mafai ona maua mai togafitiga o le radiation na faʻaaoga i aso ua tuanaʻi e togafitia ai le kanesa o le thyroid poʻo le Hodgkin lymphoma pe mai se faʻalavelave faaniukilia.

E tele tausaga e atiaʻe ai le lukimia mai le aafia ile radiation. Tele o tagata e togafitia mo kanesa ile kanesa e le maua ile kanesa. Ma o le tele o tagata ma CML latou te le o aafia i le radiation.

E masani ona tupu le CML ile matutua ile matutua ma tamaiti.

O leukemia myelogenous tumau ua faʻavasegaina i vaega:

• Faʻasologa
• Faatelevave
• Faalavelave pa

Ole vaega faʻaumiumi e mafai ona tumau mo ni masina poʻo ni tausaga. O le faʻamaʻi ono i ai ni pe leai ni faʻailoga i lenei taimi. Tele o tagata e maua ile faʻamaʻi ile taimi lea, pe a faia suʻega ile toto na faia mo isi mafuaʻaga.

O le faʻavavevaveina vaega o se sili atu matautia vaega. Leukemia sela e tupu vave. Faʻailoga masani e aofia ai le fiva (tusa lava pe leai se faʻamaʻi), tiga ponaivi, ma se fulafula totoga.

Ole togafitia o le CML e tau atu i le taimi o faʻalavelave faʻafuaseʻi. Toto ma faʻamaʻi ono tupu ona o ponaivi gaʻo le lelei.

O isi faʻailoga mafai o se faʻalavelave faʻafuaseʻi aofia ai:

• Manuʻa
• Ova le afu (afu o le po)
• Le lavava
• Fiva
• Faʻamalosi i lalo ole taumatau taumatau i lalo mai se papala ua fulafula
• Rash - laiti nini mumu faailoga luga o le paʻu (petechiae)
• Vaivaiga

O se suʻesuʻega faʻaletino e masani ona faʻaalia ai le fulafula toto. O le aofaʻi atoa o le toto (CBC) o loʻo faʻaalia mai ai le faʻateleina o sela paʻepaʻe ma le tele o ituaiga tino o iai ma le faʻateleina o numera o papamaa. O vaega ia ole toto e fesoasoani ile faʻaputuputuga ole toto.

O isi suʻega e ono faia e aofia ai:

• Biopsy o le ponaivi
• Toto ma ponaivi suʻega suʻega mo le i ai o le Philadelphia chromosome
• Faitauga peleti

O vailaʻau e faʻatutuina le polotini e le masani ai na faia e le Philadelphia chromosome e masani ona muamua togafitiga mo le CML. O nei vailaʻau e mafai ona aveina o fualaʻau. Tagata e togafitia i nei vailaʻau e masani ona oʻo i le faʻamagaloga vave ma mafai ona tumau i le faʻamagaloina mo le tele o tausaga.

O isi taimi, chemotherapy e muamua faʻaaogaina e faʻaititia ai le paʻepaʻe toto sela pe a fai e maualuga tele i faʻamaoniga.

O le faʻalavelave faʻafuaseʻi, e faigata tele ona togafitia. Aua o loʻo i ai le maualuga tele numera o le matua matua toto sela (leukemia sela) e tetee i togafitiga.

Pau lava le vailaʻau lauiloa mo le CML o le ponaivi o le gaʻo, poʻo le suia sela sela. O le toʻatele o tagata, e le manaʻomia se taotoga ona e manuia fualaʻau faʻatulagaina. Talanoa au filifiliga ma lau oncologist.

Oe ma lau fomaʻi tausi soifua ono manaʻomia e pulea le tele o isi mataupu poʻo atugaluga i le taimi o lou kanesa kanesa, aofia ai:

• Puleaina o au fagafao i le taimi o chemotherapy
• Faʻafitauli toto
• Taumafa ia lava kalori pe a e maʻi
• Fula ma tiga i lou gutu
• Taumafa saogalemu ile taimi ole togafitiga ole kanesa

Oe mafai ona faʻafaigofieina le popolevale o maʻi i le auai i le kulupu lagolago vaega. O le fefaʻasoaaʻi ma isi e masani ona maua ni faʻafitauli ma faʻafitauli e mafai ona fesoasoani ia te oe e te le lagona ai le tuua toʻatasi.

O vailaʻau faʻatulagaina ua faʻaleleia atili ai le vaʻai a tagata e iai le CML. A o faʻailoga ma faʻailoga o le CML e alu 'ese ma taulia le toto ma ponaivi gaʻo biopsy foliga masani, o le tagata e mafaufau i le faʻamagaloga. Tele o tagata e mafai ona tumau i le faʻamagaloga mo le tele o tausaga aʻo i luga o lenei vailaʻau.

O sela sela poʻo ponaivi tui e masani ona mafaufauina i tagata o latou faʻamaʻi e toe foʻi mai pe sili atu foi le leaga a o inuina muamua vailaʻau. E mafai foi ona fautuaina le tuiina mo tagata ua maua i le saoasaoa o le laasaga poʻo le pa o le faalavelave.

O faʻalavelave faʻafuaseʻi e mafai ona iʻu ai i faʻafitauli, e aofia ai faʻamaʻi, toto, vaivai, le malamalama i le fiva, ma faʻamaʻi fatu. Chemotherapy mafai ona i ai afaina ogaoga, faʻalagolago i fualaʻau na faʻaaogaina.

Aloese mai le aafia i le radiation pe a mafai.

CML; Leukemia myeloid faaumiumi; CGL; Leukemia masani o le granulosittic; Leukemia - masani granulocytic

• Tui ivi ivi - faʻateʻaina

• Manaʻoga ivi
• Leukemia faaumiumi myelosittic - vaaiga faʻa-microscopic
• Leukemia masani ole myelocytic
• Leukemia masani ole myelocytic

Kantarjian H, Cortes J. Chronic myeloid leukemia. I: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, eds. Abeloff's Clinical Oncology. 6th ed. Filatelefia, PA: Elsevier; 2020: chap 98.

'Upega Tafaʻilagi a le National Cancer Institute. Togafitiga myelogenous leukemia togafitiga (PDQ) soifua maloloina polofesa lomiga. www.cancer.gov/types/leukemia/hp/cml-treatment-pdq. Faʻafouina Fepuari 8, 2019. Avanoa ia Mati 20, 2020.

'Upega Tafaʻilagi National Comprehensive Cancer Network. NCCN togafitiga faʻataʻitaʻi faʻataʻiala i oncology: (NCCN taiala) .Chronic myeloid leukemia. Faʻamatalaga 3.2020. www.nccn.org/professionals/physician_gls/pdf/cml.pdf. Faʻafouina Ianuari 30, 2020. Avanoa ia Mati 23, 2020.

Radich J. Chronic myeloid kanesa. I totonu: Goldman L, Schafer AI, eds. Faʻafomaʻi Goldman-Cecil. 26th lomiga. Filatelefia, PA: Elsevier; 2020: chap 175