Ituaiga o chemotherapy
Chemotherapy o le faʻaaogaina o vailaʻau e togafitia kanesa. Chemotherapy fasiotia sela kanesa. E mafai ona faʻaaogaina e faʻamalolo ai le kanesa, fesoasoani e taofi mai le pepesi, pe faʻaititia ai faʻailoga.
I nisi tulaga, tagata e togafitia i le tasi ituaiga o chemotherapy. Ae masani, tagata maua sili atu ma le tasi ituaiga o chemotherapy i le taimi. E fesoasoani lea e osofaʻi le kanesa i auala eseʻese.
O togafitiga faʻapitoa ma tui puipuia o isi togafitiga o le kanesa e faʻaaoga vailaʻau e togafitia ai kanesa.
E masani ona galue le chemotherapy ile fasioti ole kanesa ma isi sela masani. Togafitiga faʻataʻatitia ma tui puipuia e leai i luga i luga faʻapitoa faʻatulagaina (mole mole) i totonu poʻo sela kanesa.
Ole ituaiga ma fualaʻau ole chemotherapy e tuʻuina atu e lau fomaʻi ia te oe e faʻamoemoe ile tele o mea eseese, e aofia ai:
- Le ituaiga kanesa o loʻo ia te oe
- Le mea na aliali mai ai le kanesa i lou tino
- Ole a foliga mai o sela ole kanesa i lalo ole microscope
- Pe ua sosolo le kanesa
- Lou tausaga ma le soifua maloloina lautele
O sela uma i le tino e tupu e ala i le vaevaeina i ni sela se lua, pe vaeluaina. O isi e vaevae e toe faaleleia mea ua faaleagaina i le tino. E tupu le kanesa pe a iai se mea e mafua ai ona fevaevaeaʻi sela ma tutupu aʻe i fafo o le taofiofia. Latou te tuputupu aʻe e fai ma vaega tele o sela, poʻo le tumo.
Chemotherapy osofaʻia vaevaega vaeluaina. Lona uiga e sili atu le oti i sela kanesa nai lo sela masani. O nisi ituaiga o togafitiga o le chemotherapy e faʻaleagaina ai mea totino i totonu o le sela e taʻu atu ai ia te ia pe faʻapefea ona kopi pe toe faʻaleleia ia lava. O isi ituaiga poloka vailaʻau o le sela manaʻomia e vaevaeina.
O nisi sela masani i le tino e vaevaeina soo, pei o lauulu ma paʻu sela. O nei sela e ono fasiotia foi e le chemo. O le mafuaʻaga lena e ono mafua ai aʻafiaga pei o le paʻu o lauulu. Ae o le tele o sela masani e mafai ona toe maua pe a maeʻa togafitiga.
E i ai le sili atu nai lo 100 vailaʻau chemotherapy eseese. Lalo o fitu ituaiga autu o chemotherapy, ituaiga o kanesa latou te togafitia, ma faʻataʻitaʻiga. O le faʻaeteetega e aofia ai mea e ese mai i masani masani togafitiga o chemotherapy.
ALKYLATING AGENTS
Faʻaaoga e togafitia ai:
- Leukemia
- Lymphoma
- Faamaʻi Hodgkin
- Myeloma tele
- Sarcoma
- Faiai
- Kanesa o le māmā, susu, ma ovary
Faʻataʻitaʻiga:
- Busulfan (Myleran)
- Cyclophosphamide
- Temozolomide (Temodar)
Lapataʻiga:
- E ono faʻaleagaina le ponaivi o le ponaivi, lea e mafai ona oʻo atu ai i le kanesa o le toto.
FUAFUAGA FAʻAVAE
Faʻaaoga e togafitia ai:
- Leukemia
- Kanesa o le fatafata, ovary, ma tamaʻaga auala
Faʻataʻitaʻiga:
- 5-fluorouracil (5-FU)
- 6-merc laptopurine (6-MP)
- Capecitabine (Xeloda)
- Gemcitabine
Lapataiga: Leai
FAʻAALIGA ANTI-TUMORA
Faʻaaoga e togafitia ai:
- Tele ituaiga kanesa.
Faʻataʻitaʻiga:
- Dactinomycin (Cosmegen)
- Bleomycin
- Daunorubicin (Cerubidine, Rubidomycin)
- Doxorubicin (Adriamycin PFS, Adriamycin RDF)
Lapataʻiga:
- Ole toto maualuga e mafai ona faʻaleagaina ai le fatu.
TOPOISOMERASE INHIBITORS
Faʻaaoga e togafitia ai:
- Leukemia
- Lumu, ovarian, gastrointestinal, ma isi kanesa
Faʻataʻitaʻiga:
- Etoposide
- Irinotecan (Camptosar)
- Topotecan (Hycamtin)
Lapataʻiga:
- E mafai e nisi ona maua se tagata i le kanesa lona lua, e taʻua o le myeloid leukemia, i totonu ole 2 i le 3 tausaga.
MITOTIC INHIBITORS
Faʻaaoga e togafitia ai:
- Myeloma
- Lymphomas
- Leukemias
- Kanesa o le susu poʻo le mama
Faʻataʻitaʻiga:
- Docetaxel (Taxotere)
- Eribulin (Halaven)
- Ixabepilone (Ixempra)
- Paclitaxel (Taxol)
- Vinblastine
Lapataʻiga:
- Sili atu ono nai lo isi ituaiga o chemotherapy mafua ai tiga tiga neʻi leaga.
'Upega Tafaʻilagi a le Sosaiete o Kanesa. Faʻafefea galue chemotherapy vailaʻau. www.cancer.org/treatment/treatments-and-side-effects/treatment-types/chemotherapy/how-chemotherapy-drugs-work.html. Faʻafouina Novema 22, 2019. Avanoa ia Mati 20, 2020.
Collins JM. Kanesa vailaʻau. I: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, eds. Abeloff's Clinical Oncology. 6th ed. Filatelefia, PA: Elsevier; 2020: chap 25.
'Upega Tafaʻilagi a le National Cancer Institute. Lua o le lisi o vailaʻau kanesa. www.cancer.gov/about-cancer/treatment/drugs. Avanoa ia Novema 11, 2019.
- Kanesa Chemotherapy