Maʻi pipisi

Malignant hyperthermia (MH) o se faʻamaʻi e mafua ai le vave oso i luga o le tino vevela ma ogaoga maso maso pe a maua e se tasi ma MH maua faʻatele vai faagase. MH e pasi i totonu o aiga.

Hyperthermia o lona uiga maualuga tino vevela. O lenei tulaga e le tutusa ma hyperthermia mai faʻalavelave faʻafuaseʻi e pei o le vevela stroke poʻo faʻamaʻi.

MH ua mautofi. Naʻo le toʻatasi matua e tauʻaveina le faʻamaʻi mo se tamaititi e maua ai le tuutuuga.

E ono tupu faʻatasi ma isi faʻamaʻi o maso ua tuufaasolo mai, pei ole multiminicore myopathy male tutotonu o faʻamaʻi.

Faʻailoga o le MH aofia ai:

• Toto
• Pepe enaena enaena (ona o le maso maso e taʻu o le myoglobin i le miaga)
• E tiga le maso e aunoa ma se mafuaaga mautinoa, pei o le faʻamalositino poʻo le manuʻa
• Maʻaʻa maso ma maaʻa
• Tulai i le vevela o le tino i le 105 ° F (40.6 ° C) pe maualuga atu

E masani ona maua le MH pe a maeʻa ona tuiina se tagata i le taimi o le taotoga.

Atonu ei ai se talaʻaga aiga o MH poʻo le faʻamatalaina maliu i le taimi o vai faagase.

Atonu e saoasaoa ma masani a le tagata le tata o le fatu.

O suʻega mo le MH e ono aofia ai:

• Suʻesuʻega ole faʻaputuga ole toto (PT, poʻo le prothrombin taimi; PTT, poʻo se vaega ole taimi ole thromboplastin)
• Toto vaega kemisi, aofia ai CK (creatinine kinase, lea e maualuga atu i le toto pe a faʻatamaia maso i le taimi o le faʻamaʻi o le maʻi)
• Faʻataʻitaʻiga kenera e vaʻai ai faʻaletonu i genes e fesoʻotaʻi ma le faʻamaʻi
• Maso biopsy
• Myoglobin mimi (maso polotini)

I le vaitaimi o le MH, o le vailaʻau e taʻua o le dantrolene e masani ona tuʻuina atu. O le afifiina o le tagata i se ie afu malulu e mafai ona fesoasoani e faʻaitiitia ai le fiva ma le ono aʻafia ai i ni faʻalavelave faigata.

Ina ia faʻasaoina fatugaʻo gaioiga i le taimi o se mea na tupu, le tagata ono mauaina vai i se uaua.

O nei fesoasoani e mafai ona maua ai nisi faʻamatalaga e uiga i le MH:

• Malignant Hyperthermia Association o le Iunaite Setete - www.mhaus.org
• National Organization for Rare Disorder - rarediseases.org/rare-diseases/malignant-hyperthermia
• NIH Genetics Fale Faʻasino Tusi - ghr.nlm.nih.gov/condition/malignant-hyperthermia

Faʻaauau pe le togafitia vaega mafai mafua ai fatugaʻo le lelei. O vaega e le togafitia e mafai ona afaina ai.

Nei faigata faʻalavelave mafai tutupu:

• Tupe maua
• Malepe o maso maso
• Fulafula o lima ma vae ma faʻafitauli ma le tafe o le toto ma neula galuega (compartment syndrome)
• Oti
• Le faʻaputuputuga ole toto ma le tafetoto
• Faʻafitauli o le fatu fatu
• Le manuia fatugaʻo
• Faʻaleleia o le acid i totonu o le tino vai (metabolic acidosis)
• Faʻaputuga suāvai i māmā
• Vaivai poʻo maso faʻaletino (myopathy poʻo muscular dystrophy)

A faʻapea e te manaʻomia se taotoga, taʻu i lau fomai tipitipi ma le fomai tipitipi muamua ae leʻi faia se taotoga pe a fai:

• E te iloa o oe poʻo se tasi o lou aiga na i ai faʻafitauli i le lautele vai faagase
• E te iloa e iai sau talaʻaga aiga o MH

Faʻaaogaina nisi vailaʻau mafai puipuia ai le faʻafitauli o le MH i taimi o taotoga.

Taʻu i lau fomaʻi soifua maloloina ae e te leʻi faia se taotoga ma vailaʻau masani, pe a fai o oe poʻo seisi o lou aiga MH.

Aloʻese mai fualaʻau faʻaosofia pei o cocaine, amphetamine (saosaoa), ma le fiafia. O nei vailaʻau ono mafua ai faʻafitauli e pei o le MH i tagata e maua i lenei tulaga.

O fautuaga faʻapitoa e fautuaina mo soʻo se tasi e iai le talaʻaga o le aiga o le myopathy, muscular dystrophy, poʻo le MH.

Hyperthermia - leaga; Hyperpyrexia - leaga; MH

American Association of Nurse Anesthetists. Malignant hyperthermia faʻafitauli sauniuni ma togafitiga: tulaga faʻamatalaga. www.aana.com/docs/default-source/practice-aana-com-web-documents-(all)/malignant-hyperthermia-crisis-preparedness-and-treatment.pdf?sfvrsn=630049b1_8. Faʻafouina Aperila 2018. Avanoa ia Me 6, 2019.

Kulaylat MN, Dayton MT. Faʻafitauli faigata. I totonu: Townsend CM Jr, Beauchamp RD, Evers BM, Mattox KL, eds. Sabiston Tusitusiga o Taʻotoga. 20 ed. Filatelefia, PA: Elsevier; 2017: mata 12.

Zhou J, Bose D, Allen PD, Pessah IN. Maʻi leaga hyperthermia ma maso-fesoʻotaʻi faʻaletonu. I le: Miller RD, ed. Miller Anesthesia. 8th ed. Filatelefaia, PA: Elsevier Saunders; 2015: mata 43.