Tofotofoga Down Syndrome

Anotusi

• O a suʻega o Down syndrome?
• O a mea e fai ai suʻega?
• Aisea ou te manaʻomia ai se suʻega o le Down Syndrome?
• O a ituaiga eseese o suʻega o Down syndrome?
• Ole a le mea e tupu ile taimi ole suʻega ole Down syndrome?
• Mata e tatau ona ou faia se mea e sauniuni ai mo suʻega?
• E i ai ni lamatiaga i le suʻega?
• O le a le uiga o faʻaiuga?
• E iai se isi mea e tatau ona ou iloa e uiga i suʻega Down Down?
• Faʻamatalaga

O a suʻega o Down syndrome?

Down syndrome o se faʻaletonu e mafua ai le atoatoa le mafaufau, eseʻese foliga tino, ma eseese faʻafitauli tau soifua maloloina. E mafai ona aofia ai ma faaletonu ole fatu, faʻafofoga leiloa, ma faʻamaʻi o lou toto. Down syndrome o se ituaiga o faʻamaʻi chromosome.

Chromosome o ni vaega o ou sela o loʻo i ai ou genes. O kenera o ni vaega o DNA na faʻasolo mai i lou tina ma lou tama. Latou te aveina faʻamatalaga e iloa ai ou uiga uiga ese, pei o le maualuga ma le lanu o mata.

• E masani ona maua e tagata le 46 chromosome, vaevaeina i paga e 23, i potu taʻitasi.
• O se tasi o paga uma o chromosome e sau mai lou tina, ma le isi paga e sau mai lou tama.
• I le Down syndrome, e iai le isi kopi o le chromosome 21.
• O le faʻaopopoga o le chromosome e suia ai le auala e tupu aʻe ai le tino ma le faiʻai.

Down syndrome, e faʻaigoaina foi o le trisomy 21, o le faʻamaʻi masani lea o le chromosome i le Iunaite Setete.

I ituaiga seasea e lua o Down syndrome, e taʻua o le mosaic trisomy 21 ma le translocation trisomy 21, o le faʻaopopoga o le chromosome e le faʻaalia i potu uma. O tagata e maua i nei faʻamaʻi e masani lava ona laʻititi ni uiga ma faʻafitauli tau soifua maloloina e fesoʻotaʻi ma le ituaiga masani o Down syndrome.

O suʻesuʻega o suʻesuʻega o Down Down e iloa ai e foliga mai e maua le Down Syndrome i lau pepe e leʻi fanau mai. O isi ituaiga o suʻega e faʻamaonia pe faʻaleaogaina le faʻamaoniga.

O a mea e fai ai suʻega?

O suʻega o Down syndrome e faʻaalu e suʻe ai pe faʻataʻitaʻi ai Down syndrome. Ole suʻega ole suʻega ole Down Syndrome e laitiiti pe leai foi se mea lamatia ia te oe poo lau pepe, ae le mafai ona latou taʻuina atu ia te oe pe o iai i lau pepe le Down syndrome.

O faʻataʻitaʻiga faʻapitoa i taimi o maʻito e mafai ona faʻamaonia pe faʻaleaogaina ai se faʻamaoniga, ae o faʻataʻitaʻiga e i ai laʻititi se faʻafitauli e ono mafua ai se paʻu.

Aisea ou te manaʻomia ai se suʻega o le Down Syndrome?

Ole tele o tausi soifua maloloina fautuaina le Down syndrome faʻataʻitaʻi ma / pe suʻesuʻe suʻega mo fafine maʻitaga e 35 tausaga pe sili atu. O le matua o le matua o le muamua tulaga faʻafitauli mafuaʻaga mo le mauaina o se pepe ma Down syndrome. Ua faateleina le tulaga lamatia a o faasolo ina matua se fafine. Ae e te ono aʻafia foʻi i se tulaga maualuga pe a fai na e maua se pepe ma Down syndrome ma / pe i ai se talaʻaga aiga o le faʻamaʻi.

I se faʻaopopoga, oe ono manaʻo e suʻesuʻe e fesoasoani ia oe e sauni pe a faʻalia i iʻuga e ono maua ai lau pepe i le Down Syndrome. O le iloa muamua e mafai ona avatua ia oe le taimi e fuafua ai mo le soifua maloloina ma tautua lagolago mo lau tama ma lou aiga.

Ae o suʻega e le mo tagata uma. Ae e te leʻi filifili e faʻataʻitaʻia, mafaufau pe faʻafefea ona e lagona ma poʻo le a sau mea e fai pe a maeʻa ona aʻoaʻoina faʻaiuga. E tatau ona e talanoaina au fesili ma faʻafitauli ma lau paʻaga ma lau soifua maloloina.

Afai e te leʻi faʻataʻitaʻia i le taimi o to ma pe manaʻo e faʻamaonia iʻuga o isi suʻega, atonu e te manaʻo e suʻesuʻe lau pepe pe a fai o ia ni faʻailoga o Down syndrome. E aofia ai:

• Faʻafolafola foliga ma isu
• O mata e pei o sekati e masii i luga
• Laʻititi taliga ma le gutu
• Laʻepaʻe papaʻe i mata
• Leaga maso maso
• Tolo atinae

O a ituaiga eseese o suʻega o Down syndrome?

E lua ituaiga faʻavae o suʻega o Down syndrome: suʻesuʻega ma suʻega faʻapitoa.

Ole suʻega ole Down Syndrome e aofia ai ma faʻataʻitaʻiga nei faia ile taimi o maʻito:

• Muamua siaki trimester aofia ai le suʻega ole toto e siaki ai le maualuga o nisi polotini i le toto o le tina. Afai o tulaga e le masani ai, o lona uiga e maualuga le avanoa o le pepe ua maua i le Down syndrome. O loʻo iai foʻi ma le suʻega o le ultrasound, o se faʻataʻitaʻiga o ata e tilotilo ai i le pepe e leʻi fanau mai mo faʻailoga o Down syndrome. O le suʻega e faia i le va o le 10 ma le 14 vaiaso o maʻito.
• Suʻega o le trimester lona lua. Nei o suʻega toto e vaʻai foʻi mo ni vailaʻau i le toto o le tina e ono avea ma faʻailoga o Down syndrome. O le suʻega tolu mata e suʻesuʻe ai ni vailaʻau eseese se tolu. E faia i le va o le 16th ma le 18th vaiaso o maʻito. O le suʻega quadruple screen e suʻesuʻeina mo ni mea eseese se fa ma e faia i le va o le 15th ma le 20 vaiaso o le maʻitaga. E ono okaina e lau tautua se tasi poʻo le lua o nei suʻega.

Afai o lau Down syndrome suʻesuʻe faʻaalia se maualuga avanoa o Down syndrome, oe ono manaʻo e faia se suʻega suʻesuʻega e faʻamaonia pe faʻateʻa ai se faʻamaoniga.

O suʻega o suʻesuʻega sa faia i le taimi o le maʻi e aofia ai:

• Amniocentesis, e ave ai se faʻataʻitaʻiga o suavai amniotic, o le suavai o loʻo faʻataʻamilomilo ai lau pepe e leʻi fanau mai. E masani ona faia ile va ole 15th ma le 20 vaiaso ole maʻitaga.
• Chorionic villus faʻataʻitaʻiga (CVS), e ave ai se faʻataʻitaʻiga mai le placenta, o le totoga e fafagaina ai lau pepe e leʻi fanau mai i totonu o lou faʻaʻautagata. E masani ona faia i le va o le 10 ma le 13th vaiaso o maʻito.
• Faʻataʻitaʻiga o le toto o le umbilical Percutaneous (PUBS), e ave ai le faʻataʻitaʻiga ole toto mai le faʻapau. O loʻo tuʻuina mai e le PUBS le faʻamaoniga sili o le Down Syndrome i le taimi o le maitaga, ae le mafai ona faia seʻia oʻo i le leva o le maʻitaga, ile va ole 18th male 22nd vaiaso

Down syndrome faʻamaoniga pe a uma le fanau mai:

E ono faia se suʻega toto o lau pepe e tilotilo ai i lana chromosome. O lenei suʻega e taʻu atu ai ia te oe pe o lau pepe ua maua i le Down Syndrome.

Ole a le mea e tupu ile taimi ole suʻega ole Down syndrome?

I taimi o suʻega toto, o se polofesa mo le soifua maloloina o le a ave se toto faʻataʻitaʻiga mai se uaua i lou lima, faʻaaoga ai se tamaʻi nila. A maeʻa ona tuʻu i totonu le nila, o le a faʻaputuputuina se vaega laʻititi o le toto i totonu o se faʻamaoniga poʻo se ipu. Atonu e te lagonaina sina tiga pe a alu le nila i totonu pe fafo. Lenei masani ona alu ifo i lalo o le lima minute.

Mo le muamua trimester ultrasound, o le a faʻasolosolo e se tausi soifua maloloina se ultrasound masini i luga o lou manava. E faʻaaogaina e le masini galu leo ​​e vaʻai i lau pepe e leʻi fanau mai. O lau tautua o le a siakiina le mafiafia i tua o le ua o lau pepe, o le faʻailoga o le Down syndrome.

Mo amniocentesis:

• E te taoto i lou tua i luga o le laulau suʻega.
• O lau tautua o le a siʻi se masini ultrasound i luga o lou manava. E faʻaaogaina e le ultrasound galu leo ​​e siaki ai le tulaga o lou faʻaʻautagata, placenta, ma lau pepe.
• E tuʻuina e lau tautua se nila manifinifi i totonu o lou manava ma toʻese mai sina laʻititi o le vai faʻamalosi.

Mo se faʻataʻitaʻiga o le villa chorionic (CVS):

• E te taoto i lou tua i luga o le laulau suʻega.
• O le a faʻasolosolo e lau tautua le masini ultrasound i luga o lou manava e siaki le tulaga o loʻo e iai lou tina, placenta, ma lau pepe.
• O le a aoina e lau tautua ni sela mai le placenta i se tasi o auala e lua: a le ala i lou gutu o le gutu o le fafine ma le paipa manifinifi e taʻua o le catheter, poʻo se nila manifinifi e ala atu i lou manava.

Mo faʻataʻitaʻiga toto o le toto samasama (PUBS):

• E te taoto i lou tua i luga o le laulau suʻega.
• O le a fesiitaʻi lau tautua i lau manava e siaki le tulaga o loʻo e iai lou tina, placenta, pepe, ma le faʻapipiʻi.
• O le a tuʻuina e lau tautua se nila manifinifi i totonu o le faʻapau ma aveese se tamaʻi vaega toto.

Mata e tatau ona ou faia se mea e sauniuni ai mo suʻega?

E leai ni sauniuniga faʻapitoa e manaʻomia mo suʻesuʻega o Down syndrome. Ae e tatau ona e talanoa i lau soifua maloloina e uiga i mea lamatia ma penefiti o suʻega.

E i ai ni lamatiaga i le suʻega?

E laʻititi lava le aʻafiaga o le faia ole suʻega ile toto poʻo le ultrasound. A maeʻa le suʻega ole toto, e te ono tiga pe tiga ile taimi na tuʻu ai le nila, ae ole tele o faʻailoga e vave ona alu ese.

Amniocentesis, CVS, ma PUBS suʻesuʻega e masani ona sili atu le saogalemu auala, ae latou te i ai sina laʻititi faʻalavelave e mafua ai se maʻitaga.

O le a le uiga o faʻaiuga?

E faʻatoa mafai ona faʻaalia iuga ole suʻega ole Down Syndrome pe a iai se maualuga o le ono maua o se pepe e maua i le Down syndrome, ae le mafai ona latou taʻuina atu ia te oe pe o iai i lau pepe le Down syndrome E i ai ni iʻuga e le masani ai, ae o loʻo maua ai pea le soifua maloloina pepe e leai ni faaletonu ole chromosomal poʻo ni faʻaletonu.

Afai o lau Down syndrome suʻesuʻega iʻuga e le masani ai, oe ono filifili e faia se tasi pe sili atu suʻega suʻega.

E mafai ona fesoasoani e talanoa i se faufautua o kenera aʻo leʻi suʻesuʻeina ma / pe a uma ona maua au faʻaiuga. O se faufautua kenera o se faʻapitoa aʻoaʻoina faʻapitoa i genetics ma faʻasologa genetic. E mafai ona ia fesoasoani ia te oe ia malamalama i le uiga o au iʻuga.

Aʻoaʻo atili e uiga i suʻesuʻega falesuesue, vaitau o faʻasino, ma malamalamaaga i iʻuga

E iai se isi mea e tatau ona ou iloa e uiga i suʻega Down Down?

O le tausiga o se tamaititi e maua i le Down syndrome e mafai ona avea ma luʻi, ae e tauia foi. Mauaina fesoasoani ma togafitiga mai faʻapitoa i le amataga o le olaga e mafai ona fesoasoani i lau tama e aapa atu i lona gafatia. Toatele tamaiti e maua i le Down syndrome e tutupu ae e ola maloloina ma fiafia i ni olaga.

Talanoa i lau fomaʻi ma lau fomaʻi faufautua e uiga i le faʻapitoa tausiga, punaʻoa, ma kulupu lagolago mo tagata ma Down syndrome ma o latou aiga.

Faʻamatalaga

1. ACOG: Fomaʻi Tamaʻitaʻi Soifua Maloloina [Initaneti]. Washington D.C .: American College of Obstetricians ma Gynecologists; c2017. Prenatal Genetic Diagnostic Suʻega; 2016 Sep [taʻua 2018 Jul 21]; [pe tusa ma le 3 pupuni] Avanoa mai: https://www.acog.org/Patients/FAQs/Prenatal-Genetic-Diagnostic-Tests
2. American Pregnancy Association [Initaneti]. Irving (TX): American Pregnancy Association; c2018. Amniocentesis; [faafou 2016 Sep 2; taʻua 2018 Jul 21]; [pe a ma le 2 pupuni] Avanoa mai: http://americanpregnancy.org/prenatal-testing/amniocentesis
3. American Pregnancy Association [Initaneti]. Irving (TX): American Pregnancy Association; c2018. Chorionic Villus Faʻataʻitaʻiga: CVS; [faafou 2016 Sep 2; taʻua 2018 Jul 21]; [pe a ma le 2 pupuni] Avanoa mai: http://americanpregnancy.org/prenatal-testing/chorionic-villus-sampling
4. American Pregnancy Association [Initaneti]. Irving (TX): American Pregnancy Association; c2018. Cordocentesis: Faʻataʻitaʻiga o le Toto i Umbilical (PUBS); [faafou 2016 Sep 2; taʻua 2018 Jul 21]; [pe a ma le 2 pupuni] Avanoa mai: http://americanpregnancy.org/prenatal-testing/cordocentesis
5. American Pregnancy Association [Initaneti]. Irving (TX): American Pregnancy Association; c2018. Down Syndrome: Trisomy 21; [faafou 2015 Jul; taʻua 2018 Jul 21]; [pe a ma le 2 pupuni] Avanoa mai: http://americanpregnancy.org/birth-defects/down-syndrome
6. American Pregnancy Association [Initaneti]. Irving (TX): American Pregnancy Association; c2018. Ultrasound Sonogram; [faafou 2017 Nov 3; taʻua 2018 Jul 21]; [pe a ma le 2 pupuni] Avanoa mai: http://americanpregnancy.org/prenatal-testing/ultrasound
7. Nofoaga autu mo le Faʻatonutonuina o Faamaʻi ma Initaneti [Initaneti]. Atlanta: U.S. Matagaluega o le Soifua Maloloina ma Tagata Auaunaga; Faʻamatalaga e uiga i Down Syndrome; [faafou 2018 Fepuari 27; taʻua 2018 Jul 21]; [pe a ma le 2 pupuni] Avanoa mai: https://www.cdc.gov/ncbddd/birthdefects/DownSyndrome.html
8. Nofoaga autu mo le Faʻatonutonuina o Faamaʻi ma Initaneti [Initaneti]. Atlanta: U.S. Matagaluega o le Soifua Maloloina ma Tagata Auaunaga; Fautuaina i Kenera; [faʻafouina 2016 Mar 3; taʻua 2018 Jul 21]; [pe a ma le 2 pupuni] Avanoa mai: https://www.cdc.gov/genomics/gtesting/genetic_counseling.htm
9. Lab Tofotofoga lugalaina [Initaneti]. Washington D.C .: American Association mo Vailaʻau Togafitiga; c2001–2018. Suʻesuʻega o le Chromosome (Karyotyping); [faafou 2018 Ian 11; taʻua 2018 Jul 21]; [pe a ma le 2 pupuni] Avanoa mai: https://labtestsonline.org/tests/chromosome-analysis-karyotyping
10. Lab Tofotofoga lugalaina [Initaneti]. Washington D.C .: American Association mo Vailaʻau Togafitiga; c2001–2018. Down Syndrome; [faafou 2018 Ian 19; taʻua 2018 Jul 21]; [pe a ma le 2 pupuni] Avanoa mai: https://labtestsonline.org/conditions/down-syndrome
11. Mati o Taimi [Initaneti]. White Plains (NY): Mati o Taimi; c2018. Down Syndrome; [taʻua 2018 Jul 21]; [pe tusa ma le 3 pupuni] Avanoa mai: https://www.marchofdimes.org/complications/down-syndrome.aspx
12. Merck Manual Consumer Version [Initaneti]. Kenilworth (NJ): Merck & Co. Inc. c2018. Down Syndrome (Trisomy 21); [taʻua 2018 Jul 21]; [pe tusa ma le 3 pupuni] Avanoa mai: https://www.merckmanuals.com/home/ Children-s-health-issues/chromosome-and-gene-abnormalities/down-syndrome-trisomy-21
13. NIH Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) [Initaneti]. Rockville (MD): U.S. Matagaluega o le Soifua Maloloina ma Tagata Auaunaga; Faʻafefea e tagata tausi soifua maloloina faʻamaonia Down syndrome; [taʻua 2018 Jul 21]; [pe a ma le 5 pupuni] Avanoa mai: https://www.nichd.nih.gov/health/topics/down/conditioninfo/diagnosis
14. NIH Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) [Initaneti]. Rockville (MD): U.S. Matagaluega o le Soifua Maloloina ma Tagata Auaunaga; O a masani faʻailoga o Down syndrome?; [taʻua 2018 Jul 21]; [pe a ma le 5 pupuni] Avanoa mai: https://www.nichd.nih.gov/health/topics/down/conditioninfo/symptoms
15. NIH National Human Genome Research Institute [Initaneti]. Bethesda (MD): U.S. Matagaluega o le Soifua Maloloina ma Tagata Auaunaga; Chromosome Faʻatonu; 2016 Ian 6 [taʻua 2018 Jul 21]; [pe tusa ma le 3 pupuni] Avanoa mai: https://www.genome.gov/11508982
16. NIH U.S. National Library of Medicine: Genetics Home Reference [Initaneti]. Bethesda (MD): U.S. Matagaluega o le Soifua Maloloina ma Tagata Auaunaga; Down Syndrome; 2018 Jul 17 [taʻua 2018 Jul 21]; [pe tusa ma le 3 pupuni] Avanoa mai: https://ghr.nlm.nih.gov/condition/down-syndrome
17. Iunivesite o Rochester Medical Center [Initaneti]. Rochester (NY): Iunivesite o Rochester Medical Center; c2018. Soifua Maloloina Encyclopedia: Suʻesuʻega o le Chromosome; [taʻua 2018 Jul 21]; [pe a ma le 2 pupuni] Avanoa mai: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=chromosome_analysis
18. Iunivesite o Rochester Medical Center [Initaneti]. Rochester (NY): Iunivesite o Rochester Medical Center; c2018. Soifua Maloloina Encyclopedia: Down Syndrome (Trisomy 21) i Tamaiti; [taʻua 2018 Jul 21]; [pe a ma le 2 pupuni] Avanoa mai: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=90&contentid=p02356
19. UW Soifua Maloloina [Initaneti]. Madison (WI): Iunivesite o Wisconsin Falemai ma Falemai Pulega; c2018. Soifua Maloloina Faʻamatalaga: Amniocentesis: Faʻafefea Ona Faia; [faafou 2017 Jun 6; taʻua 2018 Jul 21]; [pe a ma le 6 pupuni] Avanoa mai: https://www.uwhealth.org/health/topic/medicaltest/amniocentesis/hw1810.html#hw1839
20. UW Soifua Maloloina [Initaneti]. Madison (WI): Iunivesite o Wisconsin Falemai ma Falemai Pulega; c2018. Faʻamatalaga o le Soifua Maloloina: Chorionic Villus Sampling (CVS): Faʻafefea Ona Faia; [faafou 2017 Me 17; taʻua 2018 Jul 21]; [pe a ma le 6 pupuni] Avanoa mai: https://www.uwhealth.org/health/topic/medicaltest/chorionic-villus-sampling/hw4104.html#hw4121
21. UW Soifua Maloloina [Initaneti]. Madison (WI): Iunivesite o Wisconsin Falemai ma Falemai Pulega; c2018. Soifua Maloloina Faʻamatalaga: Down Syndrome: Suʻega ma Suʻega; [faafou 2017 Me 4; taʻua 2018 Jul 21]; [pe a ma le 8 pupuni] Avanoa mai: https://www.uwhealth.org/health/topic/major/down-syndrome/hw167776.html#hw167989
22. UW Soifua Maloloina [Initaneti]. Madison (WI): Iunivesite o Wisconsin Falemai ma Falemai Pulega; c2018. Soifua Maloloina Faʻamatalaga: Down Syndrome: Aotelega Autu; [faafou 2017 Me 4; taʻua 2018 Jul 21]; [pe a ma le 2 pupuni] Avanoa mai: https://www.uwhealth.org/health/topic/major/down-syndrome/hw167776.html
23. UW Soifua Maloloina [Initaneti]. Madison (WI): Iunivesite o Wisconsin Falemai ma Falemai Pulega; c2018. Faʻamatalaga o le Soifua Maloloina: Uluai Sailiga o le Trimester Muamua mo le Fanau Fanau; [faafou 2017 Nov 21; taʻua 2018 Jul 21]; [pe a ma le 2 pupuni] Avanoa mai: https://www.uwhealth.org/health/topic/special/first-trimester-screening-test/abh1912.html

O faʻamatalaga i luga o lenei 'upega tafaʻilagi e le tatau ona faʻaaogaina e fai ma sui o fomaʻi faʻapitoa togafitiga poʻo fautuaga. Faʻafesoʻotaʻi le au tausi soifua pe a iai ni au fesili e uiga i lou soifua maloloina.