O le a le Vogt-Koyanagi-Harada syndrome

Anotusi

• O le a le mafuaʻaga
• Faʻailoga mafai
• Faʻafefea ona fai le togafitiga

Vogt-Koyanagi-Harada Syndrome o se faʻamaʻi seasea e aʻafia ai aʻa o loʻo i ai melanocytes, pei o mata, totonugalemu o neula, taliga ma le paʻu, mafua ai le fulafula i le retina o mata, e masani ona fesoʻotaʻi ma faʻafitauli o le dermatological ma faʻalogo.

O lenei faʻamaʻi e tupu lava i talavou matutua i le va o tausaga o le 20 ma le 40, ma fafine e sili ona afaina. Togafitiga aofia ai le faʻatautaia o corticosteroids ma immunomodulator.

O le a le mafuaʻaga

O le mafuaʻaga o le faʻamaʻi e leʻi iloa, ae e talitonu o se faʻamaʻi autoimmune, lea o loʻo i ai le osofaʻiga i luga o le melanocytes, faʻalauteleina ai se faʻalavelave faʻafuaseʻi ma le muamua o T lymphocytes.

Faʻailoga mafai

O faʻailoga o lenei maʻi faʻalagolago i le tulaga oe i ai:

Tulaga Prodromal

I le taimi nei, o faʻamaʻi foliga e pei o faʻamaʻi o le fulū e aliali mai, o loʻo vaʻaia ma faʻailoga o neura e naʻo ni nai aso e gata ai. O faʻailoga e masani ai o le fiva, tiga o le ulu, meningism, niniva, niniva, tiga i autafa o mata, tinnitus, vaivaiga lautele o maso, maʻi supa i le tasi itu o le tino, faigata ona faʻamatala saʻo upu pe iloa le gagana, photophobia, masaesae, paʻu ma ulu. faʻaleagaina

Tulaga Uveitis

I lenei laasaga, o le ocular manifestations predominate, e pei o le fulafula o le retina, faʻaititia le vaʻai ma mulimuli ane toʻesea le retina. O nisi tagata e ono aʻafia foʻi faʻalogo faʻailoga pei o tinnitus, tiga ma le le faʻamafanafana i taliga.

Laasaga faaumiumi

I lenei laasaga, o foliga vaaia o le tino ma le faʻamaʻi o le tino e faʻaalia, e pei o le vitiligo, faʻasolosoloina o laumata mata, fulufulu mata, lea e mafai ona tumau mai masina i tausaga. Vitiligo foliga mai e tuʻufaʻatasi tufatufaina luga o le ulu, foliga ma ogalaau, ma mafai ona tumau.

Tulaga toe tupu

I lenei la tulaga tagata mafai ona atiaʻe faʻafuaseʻi mumu o le retina, cataract, glaucoma, choroidal neovascularization ma subretinal fibrosis.

Faʻafefea ona fai le togafitiga

Togafitiga aofia ai le faʻatautaia o maualuga tui o corticosteroids pei o prednisone poʻo prednisolone, aemaise lava i le matuitui vaega o le faʻamaʻi, mo le itiiti ifo i le 6 masina. Lenei togafitiga mafai mafua mafua teteʻe ma ate ate, ma i nei tulaga e mafai ona filifili mo le faʻaaogaina o betamethasone poʻo dexamethasone.

I tagata ia o le itu aʻafiaga o corticosteroids faia latou faʻaaoga i laʻititi le aoga inumaga le gafataulimaina, immunomodulator pei o cyclosporine A, methotrexate, azathioprine, tacrolimus po adalimumab mafai ona faʻaaogaina, na na faʻaaogaina ma lelei iʻuga.

I tulaga o teteʻe atu i corticosteroids ma i tagata latou te le tali atu foi i le togafitiga o le puipuia o le mafaufau, e mafai ona faʻaaogaina le immunoglobulin i totonu.