Kanesa o lou thyroid - kanesa o le medullary

Medullary carcinoma o le tiroida o le kanesa o le tiro totoa e amata i sela na faʻasaʻolotoina le homone e taʻua o le calcitonin. O sela na e taʻua o sela "C". O le thyroid gland o loʻo i totonu o le pito i luma o lou ua i lalo.

Le mafuaʻaga o medullary carcinoma o le thyroid (MTC) e leʻo iloa. E seasea lava ona maua le NAF. E mafai ona tupu i tamaiti ma tagata matutua.

E le pei o isi ituaiga kanesa o le thyroid, o le MTC e tau le maua mai i le radiation therapy i le ua ua tuʻuina atu e togafitia ai isi kanesa i taimi o tamaititi.

E lua ituaiga o NAF:

• Sporadic MTC, e le tamoʻe i totonu o aiga. Tele o NAF e feololo. Lenei fomu e masani lava ona aʻafia tagata matutua.
• Heritori MTC, o loʻo tamoʻe i totonu o aiga.

E tele lou aʻafiaga mo lenei ituaiga kanesa peʻa e maua:

• O se talaʻaga aiga o le NAF
• O se talaʻaga aiga o le tele endocrine neoplasia (MEN)
• O le muamua talaʻaga o pheochromocytoma, mucosal neuromas, hyperparathyroidism poʻo pancreatic endocrine tumors

O isi ituaiga kanesa kanesa e aofia ai:

• Anaplastic kanesa o le tiroida
• Follicular tumo o lou totoa
• Papillary kanesa o le thyroid
• O lou thyroid lymphoma

E masani ona amata le MTC ose tamaʻi kulo (nodule) ile kelu tiroida. E ono iai foʻi le fula o le ua i le ua. O lona iʻuga, auga e mafai ona aofia ai:

• Fula o le ua
• Aulelei
• Manava manava ona o le vaiti o vaalele
• Mama
• Mama i le toto
• O le manava tata ona o le maualuga o le tulaga o le calcitonin

O lau fomaʻi tausi soifua o le a faia se faʻataʻitaʻiga tino ma fesili e uiga i ou faʻailoga ma talaʻaga faʻasolopito.

O suʻega e mafai ona faʻaaoga e suʻe ai le MTC e aofia ai:

• Suʻega ole Calcitonin toto
• CEA toto suʻega
• Suʻega ole gafa
• Biopsy o lou thyroid
• Ultrasound o le thyroid ma lymph nodes o le ua
• Pet scan

Tagata e iai le MTC e tatau ona siakiina mo nisi faʻamaʻi, aemaise lava pheochromocytoma ma parathyroid tumors ma parathyroid tumors.

Togafitiga aofia ai taotoga e aveʻese le thyroid gland ma lata ane lymph node. Talu ai o le tuma e le masani ai lea, o le taotoga e tatau ona faia e se fomai tipitipi o ia e masani i lenei ituaiga o kanesa ma le poto masani i le taotoga manaʻomia.

O isi togafitiga o le a faʻalagolago i lau tulaga maualuga o le kalama. O le siʻitia i luga o tulaga faʻavaʻa o le canonitini e ono faʻaalia ai le fou o le kanesa.

• Chemotherapy ma radiation e le galue lelei mo lenei ituaiga o kanesa.
• O le susulu e faʻaaogaina i nisi tagata pe a uma taotoga.
• Ole togafiti fou e mafai ona faʻaititia ai le tuputupu aʻe o le tumo. E mafai e lau tautua ona faʻamatala atili atu ia te oe mea nei, pe a manaʻomia.

Latalata i aiga o tagata ua faʻamaonia e iai ituaiga tupuʻaga o le MTC o loʻo tele le lamatiaga o lenei kanesa ma e tatau ona talanoaina ma latou e saunia.

Oe mafai ona faʻafaigofieina le popolevale o maʻi i le auai i le kulupu lagolago vaega. O le fefaʻasoaaʻi ma isi e masani ona maua ni faʻafitauli ma faʻafitauli e mafai ona fesoasoani ia te oe e te le lagona ai le tuua toʻatasi.

Ole toʻatele o tagata e iai le NAF e ola pe a ma le 5 tausaga talu ona faʻamaonia, faʻamoemoeina ile tulaga ole kanesa. O le 10-tausaga ola fua faatatau o 65%.

Faʻafitauli e ono aofia ai:

• Ua sosolo le kanesa i isi vaega o le tino
• Parathyroid glands e faʻafuaseʻi ona aveʻesea i le taimi o taotoga

Valaʻau lau tautua peʻa iai ni faʻailoga o le MTC.

Puipuiga atonu e le mafai. Ae, o le mataala i mea e ono lamatia ai, ae maise lava lou talaʻaga aiga, ono faʻatagaina mo vave siaki ma togafitiga. Mo tagata o loʻo i ai se malosiʻaga aiga talaʻaga o le MTC, o le filifiliga e aveʻese le tiroida mafai ona fautuaina. E tatau ona e talanoaina ma le faʻaeteete lenei filifiliga ma se fomaʻi e masani lelei ma lea faʻamaʻi.

Thyroid - medullary kanesa; Kanesa - thyroid (medullary carcinoma); NAF; O lou nifo nodule - medullary

• Kanesa o lou thyroid - CT scan
• Kelu tiroida

Jonklass J, Cooper DS. Thyroid I totonu: Goldman L, Schafer AI, eds. Faʻafomaʻi Goldman-Cecil. 26th lomiga. Filatelefia, PA: Elsevier; 2020: mata 213

'Upega Tafaʻilagi a le National Cancer Institute. Togafitiga o le kanesa o lou toto (tagata matua) (PDQ) - soifua maloloina polofesa. www.cancer.gov/types/thyroid/hp/thyroid-treatment-pdq. Faʻafouina Ianuari 30, 2020. Avanoa ia Mati 6, 2020.

Smith PW, Hanks LR, Salomone LJ, Hanks JB. Thyroid I totonu: Townsend CM Jr, Beauchamp RD, Evers BM, Mattox KL, eds. Sabiston Tusitusiga o Taʻotoga. 20 ed. Filatelefaia, PA: Elsevier Saunders; 2017: mata 36.

Viola D, Elisei R. Faʻatonutonuina o le kanesa o lou toto ua oʻo i le kanesa. Endocrinol Metab Clin North Am. 2019; 48 (1): 285-301. PMID: 30717909 pubmed.ncbi.nlm.nih.gov/30717909/.

Wells SA Jr, Asa SL, Dralle H.Faʻataʻitaʻi le American Tyroid Association taiala mo le puleaina o medullary thyroid carcinoma. Thyroid. 2015; 25 (6): 567-610. PMID: 25810047 pubmed.ncbi.nlm.nih.gov/25810047/.