Tusitala: Marcus Baldwin
Aso O Foafoaga: 21 Iuni 2021
Faafouga Aso: 17 Novema 2024
Anonim
Ankylosing spondylitis - causes, symptoms, diagnosis, treatment, pathology
Ata: Ankylosing spondylitis - causes, symptoms, diagnosis, treatment, pathology

Ankylosing spondylitis (AS) o se ituaiga masani o le gugu. E tele afaina ai ponaivi ma sooga i le pito o le tuasivi e fesoʻotaʻi ma le pelvis. O nei soʻoga mafai ona fulafula ma mu. I le aluga o taimi, o le afaina ponaivi ponaivi ono auai faʻatasi.

AS o le autu sui o se aiga o tutusa ituaiga o gugu ua taʻua o le spondyloarthritis. O isi sui e aofia ai le gugu o le psoriatic, gugu o le manava o le manava manava ma galu gaioiga. O le aiga o gugu e foliga mai e taatele ma aafia ai oʻo atu i le 1 i le 100 tagata.

Ole mafuaʻaga ole AS e leʻo iloa. E foliga mai e tele se sao a Genes. Tele o tagata ma AS e lelei mo le HLA-B27 gafa.

O le faʻamaʻi e masani ona amata i le va o le 20 ma le 40 tausaga, peitaʻi e ono amata a o leʻi oʻo i le 10. E sili atu le afaina o aliʻi nai lo fafine.

AS amata i lalo maualalo tua tiga e sau ma alu. Paʻu maualalo tua e maua i le tele o taimi pe a faʻagasolo le tulaga.

  • O le tiga ma le maaʻa e sili atu le leaga i le po, i le taeao, pe a e le toaga i le lotu. O le le toʻafilemu e ono fafagu ai oe mai le moe.
  • E masani ona sili atu le tiga ile faʻamalositino poʻo le faʻamalositino.
  • Paʻu tua e ono amata i le va o le pelvis ma tuasivi (sacroiliac sooga). I le aluga o taimi, e ono aofia ai uma poʻo se vaega o le tuasivi.
  • O lou pito i lalo e ono avea ma laʻititi fetuutuunai. I le aluga o taimi, atonu e te tu ai i se tulaga faanounou i luma.

O isi vaega o lou tino e ono aʻafia e aofia ai:


  • O sooga o tauʻau, tulivae ma tapuvae, atonu e fulafula ma tiga
  • O sooga i le va o ou ivi asoaso ma le susu, ina ia e le mafai ona faʻalauteleina lou fatafata atoa
  • O le mata, atonu e fulafula ma mumu

O le lelava o se faʻailoga masani foʻi.

Faʻailoga masani e aofia ai:

  • Fiva laitiiti

AS ono tupu ma isi tulaga, pei o:

  • Suka
  • Ulcerative colitis poʻo Crohn faʻamaʻi
  • Faʻasolosolo poʻo tumau mata pupuga (iritis)

O suʻega e mafai ona aofia ai:

  • CBC
  • ESR (o se fuataga o le fulafula)
  • HLA-B27 antigen (o loʻo vaʻaia le kenera fesoʻotaʻi i ankylosing spondylitis)
  • Rheumatoid vaega (lea e tatau ona le lelei)
  • X-ray o le tuasivi ma pelvis
  • MRI o le tuasivi ma pelvis

E mafai e lau fomaʻi tausi soifua ona faʻatonu vailaʻau e pei ole NSAID e faʻaititia ai le fulafula ma le tiga.


  • O NSAID e mafai ona faʻatau i luga ole laulau (OTC). E aofia ai ma le aspirin, ibuprofen (Advil, Motrin), ma naproxen (Aleve, Naprosyn).
  • O isi NSAID e faʻatonuina e lau tautua.
  • Talanoa i lau tautua poʻo le faletalavai ae leʻi faʻaaogaina aso uma o soʻo se NSAID faʻatau-i luga o le fata.

Oe ono manaʻomia foʻi ni vailaʻau malosi e faʻatonutonu ai le tiga ma le fulafula, pei o:

  • Corticosteroid togafitiga (pei o prednisone) faʻaaogaina mo puʻupuʻu taimi
  • Sulfasalazine
  • O le biologic TNF-taofiofia (pei o etanercept, adalimumab, infliximab, certolizumab po golimumab)
  • O le biologic inhibitor o le IL17A, secukinumab

Taotoga, pei o suilapalapa suia, mafai ona faia pe a tiga poʻo soʻoga soʻoga ogaoga.

O faʻamalositino e mafai ona fesoasoani e faʻaleleia ai le tulaga o le tino ma le manava. Ole taoto faʻamafa i lou tua i le po e mafai ona fesoasoani ia te oe e tausi ai se tulaga masani.

O le ala o le faʻamaʻi e faigata ona valoia. I le aluga o taimi, faʻailoga ma faʻailoga o AS flareup (toe foʻi) ma filemu i lalo (remission). Tele o tagata e mafai ona galulue lelei seʻi vagana ua latou maua le tele o le faʻaleagaina o suilapalapa poʻo le tuasivi. O le faʻatasia o se vaega lagolago o isi ma le faʻafitauli e tasi e masani ona fesoasoani.


Togafitiga ma le NSAID masani ona faʻaititia le tiga ma le fulafula. Togafitiga ma TNF taofiofia vave i le faamai foliga mai e telegese alualu i luma o le tuasivi gugu.

E seasea lava, tagata ei ai ankylosing spondylitis ono i ai ni faʻafitauli ma:

  • Psoriasis, o se faʻamaʻi masani o le paʻu
  • Fula i le mata (iritis)
  • Fula i le puta (colitis)
  • Fati masani ole fatu
  • Viliina poʻo le mafiafia o le tino sela
  • Faʻailogaina pe mafiafia o le alatoto fatu aortic
  • Manuʻa manuʻa ua uma ina ua paʻu

Valaʻau lau tautua pe a fai:

  • Oe i ai faʻailoga o ankylosing spondylitis
  • Oe i ai ankylosing spondylitis ma atiina ae fou faʻailoga i taimi o togafitiga

Spondylitis; Spondyloarthritis; HLA - Spondylitis

  • Auivi tuasivi
  • Spondylosis o le faʻaʻautagata

Gardocki RJ, Park AL. Faʻaletonu faʻaletonu o le ponaivi ma le lumbar tua. I le: Azar FM, Beaty JH, Canale ST, eds. Campbell's Operative Orthopedics. 13th lomiga. Filatelefia, PA: Elsevier; 2017: mata 39.

Inman RD. O le spondyloarthropathies. I totonu: Goldman L, Schafer AI, eds. Faʻafomaʻi Goldman-Cecil. 26th lomiga. Filatelefia, PA: Elsevier; 2020: chap 249.

van der Linden S, Brown M, Gensler LS, Kenna T, Maksymowych WP, Taylor WJ. Ankylosing spondylitis ma isi ituaiga o axial spondyloarthritis. I totonu: Firestein GS, Budd RC, Gabriel SE, Koretzky GA, McInnes IB, O'Dell JR, eds. Firestein & Kelly's Textbook of Rheumatology. 11th lomiga. Filatelefia, PA: Elsevier; 2021: mata 80.

Ward MM, Deodhar A, Gensler LS, et al. 2019 Faʻaleleia o le American College of Rheumatology / Spondylitis Association of America / Spondyloarthritis Research and Treatment Network Fautuaina mo le togafitiga o ankylosing spondylitis ma nonradiographic axial spondyloarthritis. Togafitiga o le gaugau (Hoboken). 2019; 71 (10): 1285-1299. PMID: 31436026 pubmed.ncbi.nlm.nih.gov/31436026/.

Werner BC, Feuchtbaum E, Shen FH, Samartzis D. Ankylosing spondylitis o le faʻaautagata. I le: Shen FH, Samartzis D, Fessler RG, eds. Tusitusiga o le Cervical Spine. Filatelefaia, PA: Elsevier Saunders; 2015: mata 28.

Mataupu O Potu

Le mea e tatau ona e iloa ae e te leʻi mauaina se 'ataʻata

Le mea e tatau ona e iloa ae e te leʻi mauaina se 'ataʻata

O le a le ituaiga tuia o lenei?O le tatui o foliga ataata i totonu o lau frenulum, o le fa i laʻititi o le paʻu e fe oʻotaʻi lou laugutu i luga i lou kapulamu i luga. O lenei tatui e le mafai ona vaa...
E V8 Lelei mo Oe?

E V8 Lelei mo Oe?

O ua o fualaʻau ua avea ma pi ini i tele i nei a o. V8 atonu o le ili lauiloa o ituaiga fualaʻau ua. E feaveaʻi, au i ituaiga e ee e uma, ma ua faʻaigoaina o le mafai ona fe oa oani ia te oe e feiloaʻ...