Rhabdomyolysis

Rhabdomyolysis o le malepe o maso maso e mafua ai le faʻasaʻolotoina o maso maso i totonu o le toto. O nei vailaʻau e leaga i le fatugao ma masani ai mafua ai faʻaleagaina fatugaʻo.

A faʻaleagaina le maso, ona faʻasaʻolotoina lea o le polotini e taʻua o le myoglobin i totonu o le alatoto. Ona faʻamamaina ese lea mai le tino e fatugaʻo. Myoglobin vaevaeina i totonu o mea e mafai ona faʻaleagaina sela fatugaʻo.

Rhabdomyolysis ono mafua mai i se manuʻa poʻo seisi lava tulaga e faʻaleagaina ai auivi maso.

Faʻafitauli e ono mafua ai lenei faʻamaʻi aofia ai:

• Manua poʻo le tuʻimomomo manuʻa
• Faʻaogaina o vailaʻau pei o cocaine, amphetamines, statins, heroin, poʻo le PCP
• Faʻamaʻi o maso maso
• Ogaoga o le vevela o le tino
• Ischemia poʻo le oti o maso maso
• Maualalo tulaga phosphate
• Faoa faamalosi po o le tete maso
• Galue malosi, e pei o le marathon tamoʻe poʻo calisthenics
• Umi umi taotoga
• Faʻamamaina ogaoga

Faʻailoga e ono aofia ai:

• Pogisa, mumu, pe cola-lanu mimi
• Faʻaitiitia le gaʻo o le urine
• Vaivaiga lautele
• Maso maso poʻo tiga (myalgia)
• Malu maso
• Vaivaiga o maso ua afaina

Isi faʻailoga e ono tupu i lenei faʻamaʻi:

• Le lavava
• Tiga soʻoga
• Faoa faamalosi
• Weight maua (le fuafuaina)

O se suʻega faʻaletino o le a faʻaalia ai maso poʻo musele ivi auivi.

O suʻega ia e ono faia:

• Creatine kinase (CK) tulaga
• Suka kalama
• Serum myoglobin
• Potumoli serum
• Urinalysis
• Suʻega myoglobin suʻega

O lenei faʻamaʻi ono afaina ai foʻi iʻuga o suʻesuʻega nei:

• CK isoenzymes
• Serum foafoa
• Mimi foafoa

Oe e manaʻomia le mauaina o suavai o loʻo i ai bicarbonate e fesoasoani puipuia faʻaleagaina fatugaʻo. Oe ono manaʻomia e maua vai i se uaua (IV). Nisi tagata ono manaʻomia dialysis fatugaʻo.

E mafai ona faʻatonuina e lau tausi soifua maloloina au vailaʻau e aofia ai diuretics ma le bikarbonate (pe a lava le tele o mea e maua mai i le miaga).

Hyperkalemia ma maualalo le toto suka tulaga (hypocalcemia) tatau ona togafitia loa. E tatau foi ona togafitia fatugaia.

O le iʻuga e faʻamoemoe i le aofaʻi o le afaina o fatugaʻo. Matuia fatugao toilalo tupu i le tele o tagata. Ole togafitia ile taimi e maeʻa ai ole rhabdomyolysis ole a faʻaititia ai le ono afaina o fatugaʻo tumau.

O tagata e mama a latou mataupu e ono toe foʻi i a latou gaioiga masani i totonu o nai vaiaso i le masina. Peitai, o nisi tagata faʻaauau pea ona i ai faʻafitauli ma le lelava ma maso tiga.

Faʻafitauli e ono aofia ai:

• Matuia nativa tubular
• Ogaoga le afaina o le fatu
• Le lelei le faʻapaleni vailaʻau ile toto
• Teʻi (maualalo le toto maualuga)

Valaʻau lau tautua pe a iai ni faʻailoga o le rhabdomyolysis.

Rhabdomyolysis mafai ona 'alofia e:

• Inu i le tele o vai pe a uma le faʻamalositino malosi.
• Aveʻesea o isi lavalava ma faʻatofuina le tino i vai malulu i le tulaga o le vevela vevela.

• Anatomia fatugaʻo

Haseley L, Jefferson JA. Pathophysiology ma etiology ogaoga fatugaʻo manuʻa. I le: Feehally J, Floege J, Tonelli M, Johnson RJ, eds. Faʻamatalaga auʻiliʻi 6th ed. Filatelefia, PA: Elsevier; 2019: mata 66.

O'Connor FG, Deuster PA. Rhabdomyolysis. I totonu: Goldman L, Schafer AI, eds. Faʻafomaʻi Goldman-Cecil. 25th lomiga. Filatelefia, PA: Elsevier; 2020: chap 105.

Parekh R. Rhabdomyolysis. I: Puipui RM, Hockberger RS, Gausche-Hill M, eds. Togafitiga Faʻafuaseʻi a Rosen: Faʻataʻitaʻiga ma Togafitiga Faʻafomaʻi. 9th ed. Filatelefia, PA: Elsevier; 2018: mata 119.