Glomerulonephritis
Glomerulonephritis o se ituaiga o faʻamaʻi fatugaʻo le vaega o ou fatugaʻo e fesoasoani e faʻamama otaota ma vai mai le toto ua faʻaleagaina.
Ole vaega ole faʻamamaina ole fatugao e taʻua ole glomerulus. E tofu fatuga ma afe o glomeruli. O le glomeruli fesoasoani i le tino faʻateʻa esea mea leaga.
Glomerulonephritis ono mafua mai i faʻafitauli ma le tino o le tino puipuia. O le tele o taimi, o le mafuaʻaga tonu o lenei tulaga e le o iloa.
Faʻaleagaina i le glomeruli mafua ai le toto ma porotini e leiloa i le miaga.
O le tulaga ono tupu vave, ma fatugao gaioiga ua leiloa i totonu o vaiaso po o masina. E taʻua lea ole glomerulonephritis e vave ona alualu i luma.
O nisi tagata e maua i le glomerulonephritis faaumiumi e leai se talaaga o faamaʻi fatugaʻo.
Ole mea lea e ono faʻateleina ai lou aʻafiaga mo lenei tulaga:
- Toto poʻo le faʻafitauli o le tino lymphatic
- Faʻaalia i meaola o le hydrocarbon solvents
- Talaʻaga o le kanesa
- O faʻamaʻi pipisi e pei o papala toto, siama, faʻamaʻi fatu, poʻo le papala
Tele tuʻuga mafuaʻaga pe faʻateleina le aʻafiaga o le glomerulonephritis, aofia ai:
- Amyloidosis (faʻaletonu o le polotini e taʻua o le amyloid e fausiaina i totonu o totoga ma aʻa)
- Faʻaletonu e afaina ai le tamaʻi potu i lalo o le potu, o le vaega o le fatugaʻo e fesoasoani e faʻamama otaota ma faʻasili vai mai le toto
- Faʻamaʻi toto toto, pei o le vasculitis poʻo le polyarteritis
- Glomerulosclerosis faʻatulagaina vaega (maʻila o le glomeruli)
- Aneti-glomerular maualalo faʻamaʻi membrane (faʻaletonu o le immune system osofaʻia le glomeruli)
- Syndrome analgesic nephropathy syndrome (fatugaʻo faamaʻi ona o le mamafa o le faʻaaoga o tiga tiga, aemaise NSAIDs)
- Henoch-Schönlein purpura (faʻamaʻi e aofia ai lanu viole i luga o le paʻu, tiga soʻoga, gastrointestinal faʻafitauli ma glomerulonephritis)
- IgA nephropathy (faʻafitauli o loʻo taʻua ai Antigities ua taʻua o le IgA i luga o le fatugaʻo)
- Lupus nephritis (fatuga faʻafitauli o lupus)
- Membranoproliferative GN (ituaiga o glomerulonephritis ona o le le masani ai ona fausiaina o vailaau i le fatugaʻo)
Faʻailoga masani o le glomerulonephritis o:
- Toto i le miaga (pogisa, lanu-enaena, pe enaena enaena)
- Uru fefua (ona o le tele o polotini i le miaga)
- Fula (edema) o foliga, mata, tapuvae, vae, vae, poʻo le manava
Faʻailoga mafai ono aofia ai mea nei:
- Tiga o le manava
- Toto i le puaʻi poʻo faʻamaʻa
- Mama ma le manava puʻupuʻu
- Manava tata
- Ova tele urination
- Fiva
- Lagona lautele gasegase, lelava, ma le leai o se fiaai
- Soʻoga soʻoga poʻo le maso
- Leai
O faʻailoga o faʻamaʻi masani o fatugaʻo e ono tupu aʻe i le aluga o taimi.
Faʻamalieina fatugaʻo toilalo auga mafai lemu atiaʻe.
Ona o faʻailoga e ono tupu lemu, e ono maua le faʻamaʻi pe a iai sau urinalisis le masani ai i le taimi o le tino masani poʻo le suʻega mo se isi tulaga.
Faʻailoga o le glomerulonephritis mafai ona aofia ai:
- Anemia
- Toto maualuga
- Faailoga o le faaitiitia o le fatugao gaioiga
O se biopsy fatugaʻo faʻamaonia le faʻamaoniga.
Mulimuli ane, o faʻailoga o le maʻi o le fatugao faʻamaʻi e mafai ona vaaia, e aofia ai:
- Fula namu (polyneuropathy)
- Faʻailoga o le ova o vai, e aofia ai le le masani ai fatu ma mama māmā leo
- Fula (edema)
O faʻataʻitaʻiga i ata e mafai ona faia e aofia ai:
- Suʻega CT scan
- Ultrasound fatugaʻo
- Fatafata x-ray
- Intravenous pyelogram (IVP)
Urinalysis ma isi suʻega suʻesuʻega aofia ai:
- Faʻamamaina o le Creatinine
- Suʻega o le miaga i lalo o se microscope
- Urine aofaʻi polotini
- Uric acid i le miaga
- Suʻesuʻega faʻasolosolo vai
- Mimi foafoa
- Polotini mimi
- Urine RBC
- Urine faapitoa kalave
- Osmolality Urine
Ole faʻamaʻi lenei e ono mafua ai foʻi le le lelei o faʻaiuga ile suʻesuʻeina ole toto.
- Albumin
- Antiglomerular potu i lalo potu laʻititi faʻataʻitaʻi antibody
- Antineutrophil cytoplasmic antibodies (ANCAs)
- Antinuclear antibodies
- Tuʻu ma foafoa
- Laʻasaga faʻamalieina
Togafitiga faʻalagolago i le mafuaʻaga o le faʻamaʻi, ma le ituaiga ma le ogaoga o faʻailoga. Ole faʻatonutonuina ole toto maualuga e masani lava ole pito sili ona taua ile togafitiga.
O vailaʻau e mafai ona faʻatonuina e aofia ai:
- Toto fualaʻau toto, o le tele o taimi angiotensin-liua o le iniseti inhibitors ma angiotensin receptor poloka
- Corticosteroids
- Fualaʻau e taofiofi ai le malosi puipuia
O se auala e taʻua o le plasmapheresis e mafai ona faʻaaogaina i nisi taimi mo le glomerulonephritis e mafua mai i faʻafitauli tau puipuiga. O le vaega suavai o le toto o loʻo i ai ni vailaʻau e aveʻese ae suia i vai faʻaalu i totonu poʻo le foaʻiina o le plasma (e le o iai ni vailaʻau). O le aveʻese o vailaʻau faʻamoe e ono faʻaititia ai le fulafula o totoga o le fatugaʻo.
Oe ono manaʻomia le faʻatapulaʻaina o au taumafa o sodium, vai, polotini, ma isi vailaʻau.
Tagata ma lenei tulaga e tatau ona vaʻavaʻaia ma le totoʻa mo faʻailoga o le fatu fatu le lelei. Dialysis poʻo se tuiina fatugaʻi ono iʻu ina manaʻomia.
E mafai ona e faʻamamaina le mafatiaga o maʻi e ala i lou auai i kulupu lagolago e faʻasoa ai e tagata le poto masani ma faʻafitauli.
Glomerulonephritis atonu e le tumau ma mafai ona toe faʻafoʻi, pe ono leaga atili foi. O le alualu i luma glomerulonephritis ono taitai atu i:
- Paʻu fatugaʻo
- Faʻaitiitia le gaioiga gaioiga
- Iuga-tulaga fatugaʻo faamaʻi
Afai e i ai nephrotic syndrome ma e mafai ona taofiofia, oe ono mafai foi ona faʻatonutonu isi faʻailoga. Afai e le mafai ona taofiofia, oe ono maua i le iuga-tulaga fatugaʻo faʻamaʻi.
Valaʻau lau fomaʻi pe a fai:
- Oe i ai se tulaga e faʻateleina ai lou tulaga lamatia mo glomerulonephritis
- Oe maua i faʻailoga o le glomerulonephritis
Tele mataupu o le glomerulonephritis e le mafai ona taofia. O nisi mataupu e mafai ona puipuia e ala i le 'alofia pe faʻatapulaʻaina le faʻaalia i soli tuʻufaʻatasi, mercury, ma nonsteroidal vailaʻau faʻafomaʻi (NSAIDs).
Glomerulonephritis - tumau; Nephritis faaumiumi; Glomerular faʻamaʻi; Necrotizing glomerulonephritis; Glomerulonephritis - crescentic; Crescentic glomerulonephritis; Faʻasolosolo alualu i luma glomerulonephritis
- Anatomia fatugaʻo
- Glomerulus ma nephron
Radhakrishnan J, Appel GB, DʻAgati VD. Maualuga glomerular faʻamaʻi. I: Yu ASL, Chertow GM, Luyckx VA, Marsden PA, Skorecki K, Taal MW, eds. Brenner ma Rector's Le Fatugaʻo. 11th lomiga. Filatelefia, PA: Elsevier; 2020: chap 32.
Reich HN, Cattran DC. Togafitiga o le glomerulonephritis. I: Yu ASL, Chertow GM, Luyckx VA, Marsden PA, Skorecki K, Taal MW, eds. Brenner ma Rector's Le Fatugaʻo. 11th lomiga. Filatelefia, PA: Elsevier; 2020: chap 33.
Saha MK, Pendergraft WF, Jennette JC, Falk RJ. Muamua glomerular faʻamaʻi. I: Yu ASL, Chertow GM, Luyckx VA, Marsden PA, Skorecki K, Taal MW, eds. Brenner ma Rector's Le Fatugaʻo. 11th lomiga. Filatelefia, PA: Elsevier; 2020: mata 31