HLA-B27 antigen

HLA-B27 o se suʻega toto e suʻesuʻe ai mo polotini e maua i luga o sela papaʻe. O le polotini e taʻua ole tagata leukocyte antigen B27 (HLA-B27).

Tagata leukocyte antigens (HLAs) o ni polotini e fesoasoani i le tino o le tino e iloa ai le eseesega i le va o ana lava sela ma fafo, mea leaga. Na gaosia mai i faʻatonuga e le tupuʻaga o tupuʻaga.

E manaʻomia se faʻataʻitaʻiga ole toto. O le tele o taimi, o le toto e toso mai le uaua o loʻo tu i totonu o le tulilima poʻo tua o le lima.

I le tele o tulaga, e le manaʻomia ni laʻasaga faʻapitoa e sauniuni ai mo le suʻega.

A faʻapipiʻi le nila e utu ai le toto, e te ono lagona le agavaʻa tiga, pe naʻo se tuitui poʻo se lagona tiga. A maeʻa, atonu e i ai ni faʻagatete.

E mafai e lau tausi soifua maloloina ona poloaʻi lenei suʻega e fesoasoani e faʻamaonia le mafuaʻaga o le soʻoga o tiga, maʻaʻa, poʻo le fulafula. O le suʻega ono faia faʻatasi ma isi suʻega, e aofia ai:

• C-toe faʻaola polotini
• Fua faatatau sedryation Erythrocyte (ESR)
• Rheumatoid vaega
• X-ray

HLA suʻega e faʻaaoga foi e faʻafetaui meaalofa foaʻi ma aʻa o le tagata o loʻo mauaina se totoga taotoga. Mo se faʻataʻitaʻiga, e mafai ona faia pe a manaʻomia e se tagata le tuiina o fatugaʻo poʻo le gaʻo o le ponaivi.

O se iʻuga masani (le lelei) o lona uiga e toʻesea HLA-B27.

O se suʻega lelei o lona uiga o loʻo iai HLA-B27. O loʻo fautua mai ai le sili atu i le averesi le aʻafiaga mo le atiaʻe poʻo le iai o ni faʻamaʻi autoimmune. O le faʻamaʻi autoimmune o se tulaga e tupu pe a osofaʻia sese ma faʻaleagaina e le tino puipuia le tino maloloina tino.

O se faʻaiuga lelei e mafai ona fesoasoani i lau tautua e faia se faʻamaoniga o se ituaiga o gugu e taʻu o le spondyloarthritis. Lenei ituaiga o gugu aofia ai le nei faaletonu:

• Ankylosing spondylitis
• Fiva e fesoʻotaʻi ma Crohn faʻamaʻi poʻo ulcerative colitis
• Gugu Psoriatic (gugu fesoʻotaʻi ma psoriasis)
• Galue malosi gugu
• Sacroiliitis (mumu o le sacroiliac soofaatasi)
• Uveitis

A iai ni faʻailoga poʻo ni faʻailoga o le spondyloarthritis, e mafai ona fesoasoani se suʻesuʻega lelei o le HLA-B27 e faʻamaonia ai le faʻamaoniga. Peitaʻi, o le HLA-B27 e maua i nisi tagata masani ma e le masani ona uiga o loʻo e maua i se faʻamaʻi.

O faʻafitauli mai le tosoina o le toto e laʻititi, ae mafai ona aofia ai:

• Toto tele
• Faaseʻe pe lagona le mumu o le ulu
• Hematoma (toto faʻaputuputu i lalo o le paʻu)
• Faamaʻi (o se laʻititi tulaga lamatia soʻo se taimi le paʻu ua paʻu)

Tagata leukocyte antigen B27; Ankylosing spondylitis-HLA; Gugu Psoriatic-HLA; Galue malosi gugu-HLA

• Tofotofoga toto

Chernecky CC, Berger BJ. Tagata Leukocyte Antigen (HLA) B-27 - toto. I le: Chernecky CC, Berger BJ, eds. Suʻesuʻega a le Falesuesue ma Taualumaga o Suʻesuʻega. 6th ed. St Louis, MO: Elsevier Saunders; 2013: 654-655.

Fagoaga PO. Tagata leukocyte antigen: o le tele histocompatibility faigata o le tagata. I totonu: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management e le Laboratory Metotia. 23rd ed. St Louis, MO: Elsevier; 2017: mata 49.

Inman RD. O le spondyloarthropathies. I totonu: Goldman L, Schafer AI, eds. Faʻafomaʻi Goldman-Cecil. 25th lomiga. Filatelefaia, PA: Elsevier Saunders; 2016: mata 265

McPherson RA, Massey HD. Vaaiga aoao i le puipuiga ma le puipuia o le tino. I totonu: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management e le Laboratory Metotia. 23rd ed. St Louis, MO: Elsevier; 2017: mata 43.

Faʻaalia JD. Spondyloarthritis. I: Rich RR, Fleisher TA, Shearer WT, Schroeder HW, Few AJ, Weyand CM, eds. Togafitiga Puipuiga: Mataupu Faavae ma Faʻataʻitaʻi. 5th ed. Filatelefia, PA: Elsevier; 2019: chap 57.