Tele endocrine neoplasia (MEN) I

Tele endocrine neoplasia (MEN) ituaiga I o se faʻamaʻi o le tasi po o le sili atu o le endocrine glands ua soʻona soʻosoʻo pe fausia ai se tumo. E pasi mai i aiga.

Endocrine glands e masani ona aofia ai aofia ai:

• Pankreas
• Parathyroid
• Pituitary

MEN O aʻu e mafua mai i se faʻaletonu i se kenera o loʻo ave ai le tulafono mo le polotini e taʻua o le menin. O le tulaga mafua ai tuma o eseese glands e aliali mai i le tutusa tagata, ae le tatau i le taimi e tasi.

E mafai ona tupu le faʻamaʻi i soʻo se tausaga, ma e aʻafia tutusa ai aliʻi ma fafine. O se talafaʻasolopito o aiga o lenei faʻamaʻi e tulaʻi mai ai lou tulaga lamatia.

Faʻailoga eseese mai le tasi tagata i le tagata, ma faʻalagolago i luga o le a afu o loʻo aafia. Latou te ono aofia ai:

• Tiga o le manava
• Popole
• Lanu uli, nofoa faʻatali
• Lagona fefete pe a uma taumafataga
• Mu, tiga, poʻo le fiaʻai faʻanoanoa i luga o le manava poʻo lalo pusa e faʻamalieina e antacids, susu, poʻo meaai
• Faʻaitiitia le fiafia i feusuaiga
• Le lavava
• Tigā ulu
• Le lava o taimi masina (i fafine)
• Leai o le fiaai
• Leiloa o le tino po o lauulu foliga (i alii)
• Suiga o le mafaufau po o le le mautonu
• Tiga maso
• Faanoi ma puaʻi
• Sensitivity i le malulu
• Leiloa leiloa mamafa mamafa
• Faʻafitauli vaʻai
• Vaivaiga

O le tausi soifua maloloina o le a faia se faʻataʻitaʻiga tino ma fesili fesili e uiga i lou soifua maloloina talaʻaga ma faʻailoga. O suʻega ia e ono faia:

• Toto maualuga cortisol tulaga
• CT faʻataʻitaʻi le manava
• CT scan o le ulu
• Anapogi suka suka
• Suʻega ole gafa
• Suʻega o le inisalini
• MRI o le manava
• MRI o le ulu
• Sone adrenocorticotropic homone
• Suka kalama
• Serum follicle faʻaosofia ai le homone
• Gasini oona
• Fua o le suka
• Serum luteinizing homone
• Serum parathyroid homone
• Serum prolactin
• Serum thyroid faʻaosofia loto
• Ultrasound o le ua

O taotoga e aveese ai le gland gland masani o le togafitiga o filifiliga. O vailaʻau e faʻaigoaina o le bromocriptine e mafai ona faʻaaogaina nai lo o le taotoga mo le papaleni tumors e faʻasaʻoloto ai le hormone prolactin.

O le parathyroid glands, e faʻatonutonuina ai le gaosiaina o le calcium, e mafai ona aveʻesea. Ae ui i lea, e faigata mo le tino ona faʻatonutonu tulaga o le calcium e aunoa ma nei manava, o lea la o le aofaʻi o le parathyroid aveʻesea e le faia muamua i le tele o tulaga.

O loʻo avanoa vailaʻau e faʻaititia ai le tele o le gaosia o le manava oona na mafua mai i isi tuma (gastrinomas), ma faʻaititia ai le afaina o papala.

Hormone replacement therapy e faia pe a aveʻese uma glands pe leai ni gaʻo tele o homone.

Pituitary ma parathyroid tumors e masani lava noncancerous (benign), ae o ni pancreatic tumors ono avea ma kanesa (malignant) ma salalau atu i le ate. O nei e mafai tuʻuina i lalo le ola olaga.

O faʻailoga o le papala papala faʻamaʻi, maualalo le suka i le toto, sili atu kalisiu i le toto, ma le pituitary faʻaleagaina masani ona tali lelei i togafitiga talafeagai.

E mafai ona toe foʻi mai tuma. Faʻailoga ma faʻalavelave faʻalagolago i luga o glands o loʻo aafia. O siaki masani a lau 'auʻaunaga e taua tele.

Valaʻau lau tautua pe a fai e te maitauina faʻailoga o le MEN I pe i ai sau talaʻaga aiga o lenei tulaga.

O le suʻesuʻe vavalalata aiga o tagata ua aʻafia i lenei faʻamaʻi ua fautuaina.

Wermer syndrome; TAGATA I

• Laʻau Endocrine

'Upega Tafaʻilagi National Comprehensive Cancer Network. Taʻiala faʻataʻi mo togafitiga ile oncology (NCCN guideines): neuroendocrine tumors. Faʻamatalaga 1.2019. www.nccn.org/professionals/physician_gls/pdf/neuroendocrine.pdf. Faʻafouina Mati 5, 2019. Avanoa ia Mati 8, 2020.

Newey PJ, Thakker RV. Neoplasia tele endocrine. I: Melmed S, Auchus RJ, Goldfine AB, Koenig RJ, Rosen CJ, eds. Williams Tusitusiga o Endocrinology. 14th lomiga. Filatelefia, PA: Elsevier; 2020: chap 42.

Nieman LK, Spiegel AM. Faʻafitauli polyglandular. I totonu: Goldman L, Schafer AI, eds. Faʻafomaʻi Goldman-Cecil. 26th lomiga. Filatelefia, PA: Elsevier; 2020: chap 218.

Thakker RV. Tele endocrine neoplasia ituaiga 1. I: Jameson JL, De Groot LJ, de Kretser DM, et al, eds. Endocrinology: Matutua ma Tamaiti. 7th ed. Filatelefaia, PA: Elsevier Saunders; 2016: mata 148.