Antimitochondrial antibody

Antimitochondrial antibodies (AMA) o vailaʻau (antodies) e faʻasaga i le mitochondria. O le mitochondria o se vaega taua o sela. O latou ia o le malosiaga puna i totonu o sela. O mea ia e fesoasoani e galue lelei ai sela.

Lenei tusitusiga talanoaina le suʻega toto faʻaogaina e fua ai le aofaʻi o AMA i le toto.

E manaʻomia se faʻataʻitaʻiga ole toto. E masani ona ave mai se uaua. O le auala e taʻua o le venipuncture.

Atonu e taʻu atu e lau tausi soifua maloloina ia te oe e aua le 'ai pe inu i se mea e oʻo atu i le 6 itula ao le i faia le suʻega (e masani ona faia i le po).

A faʻaofi le nila e toso le toto, o nisi tagata e lagona le feololo tiga. O isi e ono lagona naʻo se tuia poʻo se lagona tiga. A maeʻa, atonu e i ai ni faʻagatete.

Atonu e te manaʻomia lenei suʻega pe a iai ni faʻailoga o le ate. O lenei faʻataʻitaʻiga e masani ona faʻaaoga e faʻamaonia ai le cholangitis biliary muamua, na taʻua muamua o le bilier cirrhosis (PBC).

E mafai foi ona faʻaaoga le suʻega e taʻu ai le eseesega i le va o le bile system-related cirrhosis ma le ate ona o isi mafuaaga e pei o le poloka, viral hepatitis, poʻo le ava malosi cirrhosis.

E masani lava, e leai ni vailaʻau o iai.

O lenei suʻega e taua mo le faʻailoaina o le PBC. Toetoe lava uma tagata ma le tulaga o le a tofotofoina lelei. E seasea tupu se tagata e aunoa ma le tuʻuga o le a maua se iʻuga lelei. Ae ui i lea, o nisi tagata ma le lelei suʻega mo le AMA ma leai seisi faʻailoga o le ate faʻamaʻi ono alualu i luma i le PBC i le aluga o taimi.

E seasea lava, e ono maua ni faʻalavelave e mafua mai i isi ituaiga o maʻi o le ate ma nisi o faʻamaʻi o le autoimmune.

O faʻafitauli mo le tosoina o le toto e laʻititi ae mafai ona aofia ai:

• Toto tele
• Faaseʻe pe lagona le mumu o le ulu
• Hematoma (toto faʻaputuputu i lalo o le paʻu)
• Faamaʻi (o se laʻititi tulaga lamatia soʻo se taimi le paʻu ua paʻu)

• Tofotofoga toto

Beuers U, Gershwin ME, Gish RG, et al. Suiga nomenclature mo PBC: Mai le 'cirrhosis' i le 'cholangitis'. Clin Res Hepatol Gastroenterol. 2015; 39 (5): e57-e59. PMID: 26433440 www.ncbi.nlm.nih.gov/pubmed/26433440.

Chernecky CC, Berger BJ. A. I le: Chernecky CC, Berger BJ, eds. Suʻesuʻega a le Falesuesue ma Taualumaga o Suʻesuʻega. 6th ed. St Louis, MO: Elsevier Saunders; 2013: 84-180.

Eaton JE, Lindor KD. Cirrhosis biliary muamua. I totonu: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger ma Fordtran's Gastrointestinal ma le Maʻi ole: Pathophysiology / Diagnosis / Pulega. 10 ed. Filatelefaia, PA: Elsevier Saunders; 2016: mataʻi 91.

Kakar S. Peraimeri biliary cholangitis. I totonu: Saxena R, ed. Faʻapitoa Hepatic Pathology: O se Faʻataʻitaʻiga Diagnostic. 2nd ed. Filatelefia, PA: Elsevier; 2018: mata 26.

Zhang J, Zhang W, Leung PS, et al. Faʻaauau le faʻagaoioia o sela sela autoantigen-faʻapitoa i le muamua biliary cirrhosis. Hepatology. 2014; 60 (5): 1708-1716. PMID: 25043065 www.ncbi.nlm.nih.gov/pubmed/25043065.