T3RU suʻega

O le suʻega ole T3RU e fua ai le maualuga o polotini e feaveaʻi le thyroid hormone i le toto. E mafai ona fesoasoani lenei mea i lau soifua maloloina e faʻamatala uiga o T3 ma T4 toto suʻega.

Talu ai o suʻega e taʻua o le T4 toto e fai fua le suʻesuʻega ma le tiroina o le toto e fusia ai le globulin (TBG) ua avanoa nei, ua seasea faʻaaogaina nei le suʻega T3RU i nei aso.

E manaʻomia se faʻataʻitaʻiga ole toto.

O le a taʻu atu e lau tautua ia te oe pe a manaʻomia lou taofia le toe inuina o ni vailaʻau aʻo leʻi faia le suʻega e ono aʻafia ai lau faʻaiuga. Aua le taofia le inuina o se vailaʻau e aunoa ma le muamua talanoa i lau tautua.

Nisi vailaʻau e mafai faʻateleina T3RU tulaga aofia ai:

• Anabolic vailaʻau
• Heparin
• Phenytoin
• Salicylates (maualuga inumaga)
• Warfarin

Nisi vailaʻau e mafai faʻaititia T3RU tulaga aofia ai:

• Antithyroid vailaʻau
• Pamu e taofi ai le fananau mai
• Faʻalelei
• Estrogen
• Thiazides

Maitaga mafai foi faʻaititia T3RU tulaga.

O nei tulaga e mafai ona faʻaititia ai tulaga TBG (vaʻai lalo vaega "Aisea e Faia ai le Suʻega" mo nisi mea e uiga i le TBG):

• Maʻi tuga
• Faamaʻi fatugaʻo pe a leiloa porotini i le miaga (nephrotic syndrome)

O isi vailaʻau e fusifusia i polotini i le toto e mafai foi ona afaina ai faʻaiuga o le suʻega.

A faʻaofi le nila e toso le toto, o nisi tagata e lagona le feololo tiga. O isi e naʻo se tuitui poʻo se tui e lagona. A maeʻa, atonu e i ai se tuitui poʻo sina manuʻa. Lenei vave alu ese.

O lenei suʻega ua faia e siaki ai lau galue taʻimua. O le galueina o le thyroid e faʻamoemoe i le gaioiga a le tele o isi homone, e aofia ai le thyroid-stimulate hormone (TSH), T3, ma le T4.

O lenei suʻega fesoasoani e siaki le aofaʻi o T3 e mafai e le TBG ona faʻamau. TBG o se porotini e aveina le tele o T3 ma T4 i le toto.

E ono fautuaina e lau tautua se suʻega T3RU peʻa iai sau faʻailoga o le faʻafitauli o le thyroid, e aofia ai:

• Hyperthyroidism (ova tele lou thyroid)
• Hypothyroidism (le toaga galue)
• Thyrotoxic paralysis taimi (maso vaivai mafua mai i le maualuga tulaga o le thyroid hormone i le toto)

O tulaga masani e amata mai i le 24% e oʻo i le 37%.

E masani ona fesuisuiaʻi vaega eseese o tau masani ile falefaigaluega eseese. O nisi fale suesue faʻaaoga eseese fuataga pe tofotofoina eseese faʻataʻitaʻiga. Talanoa i lau tautua e uiga i le uiga o au faʻapitoa suʻega iʻuga.

Maualuga-nai lo-masani tulaga ono taʻu mai:

• Le manuia fatugaʻo
• Ova tele lou thyroid (hyperthyroidism)
• Faʻamaʻi o le nephotic
• Palapala paleni

Maualalo-nai lo-masani tulaga ono taʻu mai:

• Hepatitis matuitui (faamaʻi o le ate)
• Maitaga
• Hypothyroidism
• Faʻaaogaina o le estrogen

O iʻuga le lelei e ono mafua mai ile tofi tuʻuina mai ole maualuga ole TBG. E masani lava o le masani ole galue ole thyroid i tagata e iai le faʻamaʻi lea.

Lenei suʻega ono mafai foi ona faia mo:

• Thyroiditis faaumiumi (fulafula pe pupuga o le thyroid gland, aofia ai ma le Hashimoto faamaʻi)
• Hypothyroidism faʻaosofia i vailaʻau
• Faamaʻi tuugamau
• Tipiina thyroiditis
• Maʻi supa Thyrotoxic
• Meaʻai faʻaalu oona

E i ai laʻititi le faʻafitauli e aafia ai i lou aveina o lou toto. O alatoto ma alatoto e eseese i le tele mai le tasi tagata i le isi ma mai le tasi itu o le tino i le isi. Mauaina o se toto faʻataʻitaʻiga mai nisi tagata ono faigata sili atu nai lo isi.

O isi faʻafitauli e fesoʻotaʻi ma le tosoina o le toto e laʻititi, ae mafai ona aofia ai:

• Toto tele
• Faaseʻe pe lagona le mumu o le ulu
• Tele tui e suʻe ai uaua
• Hematoma (faʻaputuputu toto i lalo o le paʻu)
• Faamaʻi (o se laʻititi tulaga lamatia soʻo se taimi le paʻu ua paʻu)

Resin T3 aveina; T3 aveina resin; Fua faʻatatau o le homone-thyroid

• Tofotofoga toto

Guber HA, Farag AF. Iloiloga o galuega endocrine. I totonu: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management e le Laboratory Metotia. 23rd ed. St Louis, MO: Elsevier; 2017: mata 24.

Kiefer J, Mythen M, Roizen MF, Fleisher LA. Aafiaga faʻateʻia o faʻamaʻi tuʻufaʻatasi. I le: Gropper MA, ed. Miller Anesthesia. 9th ed. Filatelefia, PA: Elsevier; 2020: chap 32.

Salvatore D, Cohen R, Kopp PA, Larsen PR. Tiroida pathophysiology ma iloiloga faʻamaoniga. I: Melmed S, Auchus RJ, Goldfine AB, Koenig RJ, Rosen CJ, eds. Williams Tusitusiga o Endocrinology. 14th lomiga. Filatelefia, PA: Elsevier; 2020: mata 11.

Weiss RE, Toe faʻafoʻi S. Vaʻavaʻaia galuega a le thyroid. I totonu: Jameson JL, De Groot LJ, de Kretser DM, et al, eds. Endocrinology: Matutua ma Tamaiti. 7th ed. Filatelefaia, PA: Elsevier Saunders; 2016: mata 78.