Tusitala: Monica Porter
Aso O Foafoaga: 17 Mati 2021
Faafouga Aso: 18 Novema 2024
Anonim
Non-hodgkin lymphoma - causes, symptoms, diagnosis, treatment, pathology
Ata: Non-hodgkin lymphoma - causes, symptoms, diagnosis, treatment, pathology

Anotusi

Vaaiga aoao

Lymphoma o se ituaiga o kanesa e amata i lymphocytes. Lymphocytes o sela i le puipuiga faʻafitauli. O le Hodgkin's ma le-Hodgkin's lymphoma o ituaiga autu ia e lua o le lymphoma.

T-cell lymphoma ma le B-cell lymphoma e lua ituaiga o non-Hodgkin's lymphoma. E i ai foi se ituaiga seasea taʻua o le NK-cell lymphoma.

Faʻatasi ai ma tagata e le o ni Hodgkin lymphoma, e tusa ma le 85 pasene e maua i le B-cell lymphoma.

Togafitiga mo B-sela lymphomas e faʻavae i luga o le faʻapitoa subtype ma tulaga o faʻamaʻi.

O a subtypes o B-cell lymphoma?

E tele subtypes o B-cell lymphoma, o loʻo lemu le tuputupu aʻe (paie) ma televave tupuola (faʻamalosi), e aofia ai:

B-sela subtypeUiga o uiga
Faʻafesoʻotaʻi le tele B-cell lymphoma (DLBCL)Ole ituaiga masani lea ole lymphoma ole ole Hodgkin. O se kanesa malosi ae mafai ona togafitia e mafai ona aofia ai lymph nodes ma isi totoga.
Follicular lymphomaLenei o le lona lua sili ona taatele ituaiga luga non-Hodgkin's lymphoma. E telegese lona tupu ma masani ona amata ile lymph nodes.
Mantel sela limafomaE masani lava ona aofia ai lymph nodes, ponaivi ponovi, spleen, ma le gastrointestinal system.
Leukemia faaumiumi lymphocytic (CLL) / Laititi lymphocytic lymphoma (SLL)O lenei ituaiga e paie ma masani ona afaina ai le toto ma ponaivi ponaivi (CLL), poʻo lymph nodes ma spleen (SLL).
Peraimeri tutotonu ogatotonu lymphomaO lenei ituaiga e masani ona amata i le faiʻai poʻo le uaula. E fesoʻotaʻi ma faʻafitauli puipuia e mafua mai i le AIDS poʻo vailaʻau teteʻe e faʻaoga e sosoʻo mai le totoina o totoga.
Splenic liʻo sone B-sela lymphomaLenei o se ituaiga lemu-tuputupu ae e amata i le spleen ma ponaivi suo.
Extranodal liʻo sone B-cell lymphoma o MALTLenei ituaiga masani aofia ai le manava. E mafai foi ona tupu i mama, paʻu, thyroid, liu, poʻo le mata.
Nodal liʻo sone B-sela lymphomaLenei o se seasea, lemu-tuputupu ae ituaiga maua masani lava i le lymph node.
Burkitt lymphomaLenei o se vave-tupu ituaiga o sili atu taatele i tamaiti.
Leukemia sela selaO lenei o se ituaiga faatelegese-tupu e aafia ai le spleen, lymph nodes, ma le toto.
Lymphoplasmacytic lymphoma (Waldenstrom macroglobulinemia)Lenei o se seasea, o le lemu-tupu lymphoma o le ponaivi suo, spleen, ma lymph nodes.
Lymphoma aoga muamuaLenei o se seasea, agavaʻa ituaiga e ono tupu i tagata o loʻo iai se vaivaiga vaivai faʻamalosi tino.

Faʻavaeina

O le kanesa e faʻavaeina e tusa ma le mamao na sosolo ai mai le amataga tulaga. Ole-ole Hodgkin's lymphoma e faʻatautaia mai le 1 i le 4, ma le 4 e sili ona maualuga.


O a faʻailoga?

Faʻailoga e eseese e tusa ma le ituaiga o B-cell lymphoma ma le faʻalelei o lona tulaga. Nei o nisi o auga iloga:

  • fulafula lymph nodes i lou ua, lima, poʻo tuavae
  • tiga o le manava pe fulafula
  • tiga o le fatafata
  • tale
  • manava faigata
  • afu ma afu afu
  • paʻu pauna
  • lelava

E faʻafefea ona togafitia?

Nisi ituaiga o lymphoma e leai se faʻailoga ma le paie e le tau manaʻomia se togafitiga. Atonu e fautuaina e lau fomaʻi le mea e taʻu o le "mataala mataala." Lona uiga e te tulitataoina i nai masina uma ina ia mautinoa e leʻo alualu i luma le kanesa. I nisi tulaga, lenei mafai ona faʻaauau mo le tele o tausaga.

Togafitiga mafai ona amata pe a aliaʻe faʻailoga pe afai ei ai faʻailoga o faʻamaʻi alualu i luma. B-cell lymphoma e masani ona aofia ai le tuʻufaʻatasia o togafitiga, lea e ono suia i le aluga o taimi.

Susulu

O le faʻaaogaina o malosiʻaga malosi e faʻaalu ai le malosi, e faʻaalu ai le radiation therapy e fasioti ai sela o le kanesa ma faʻapipiʻi ai tagata. E manaʻomia le taoto pea i luga o le laulau aʻo faʻatonutonu laʻau i se tulaga saʻo i lou tino.


Mo le lemu-tupu, localized lymphoma, radiation togafitiga atonu na o oe lava manaʻomia.

Aafiaga e mafai ona aofia ai le lelava ma paʻu ita.

Chemotherapy

Chemotherapy o se togafitiga faʻasolosolo e mafai ona tuʻuina atu i le gutu poʻo le leʻo. E mafai ona faʻamaloloina ni vailaʻau mataʻutia B-cell i le chemotherapy, ae maise lava ile amataga ole maʻi.

DLBCL o se vave ola ituaiga e mafai ona togafitia ma se togafitiga togafitiga e taʻua o le CHOP (cyclophosphamide, doxorubicin, vincristine, ma le prednisone). A aumai ma le monoclonal antibody rituximab (Rituxan), e faʻaigoa ia R-CHOP. E masani ona tuʻuina i taʻamilosaga ile tele o vaiaso vavaeʻese. E faigata i le fatu, o lona uiga e le o se filifiliga pe a fai o loʻo i ai muamua ni faʻafitauli o le fatu.

O aʻafiaga o chemotherapy mafai ona aofia ai le niniva, lelava, ma leiloa lauulu.

Faʻamalologa puipuia

O vailaʻau o le biologic e fesoasoani i lau puipuiga i le kanesa. Rituximab taulaʻi polotini luga o le B-sela, faʻafaigofie ai mo le puipuiga sisitema ia iloa ma faʻaleagaina i latou. E ala i le faʻaititia o numera o sela ua maua i le kanesa ma maloloina, o le vailaʻau e unaʻia lou tino e fausia ni sela soifua maloloina fou. Lea e faʻaititia ai le toe maua mai o le kanesa.


O vailaʻau o le Radioimmunotherapy, e pei ole ibritumomab tiuxetan (Zevalin), e faia mai i monotaga o le monoclonal o loʻo feaveaʻia isotopes e faʻatino ile leitio. O le vailaʻau e fesoasoani i vailaʻau faʻapipiʻi e pipii i sela kanesa mo le tuʻuina tuusaʻo o le radiation.

Aʻafiaga o togafitiga puipuia e mafai ona aofia ai le maualalo papaʻe sela sela, lelava, ma faʻamaʻi pipisi.

Tauiina sela sela

O le totoina sela sela e aofia ai le suia o lou ponaivi i le suo mai se soifua maloloina foai. Muamua, e te manaʻomia le maualuga o vailaʻau ole chemotherapy poʻo le radiation e tineia ai lou tino puipuia, faʻaleagaina sela o le kanesa, ma faʻaavanoa ai le suauʻu fou. Ina ia agavaʻa, oe tatau ona lava le soifua maloloina e tatalia lenei togafitiga.

O aʻafiaga e mafai ona aofia ai faʻamaʻi, anemia, ma le teʻena o le ponaivi fou.

E i ai ni faʻafitauli faigata?

O le Lymphomas e faʻavaivaia ai lau faʻamalosi tino, ma atili ai ona afaina oe i faʻamaʻi pipisi. Nisi togafitiga mo lymphoma mafai mafua mafua faʻalavelave e pei o:

  • leai se fanau
  • fatu, māmā, fatugaʻo, ma faʻamaʻi o lou toto
  • maʻi suka
  • kanesa lona lua

B-cell lymphomas mafai ona tupu ma salalau i mamao totoga.

Faʻafefea le toe faʻaleleia?

Nisi ituaiga o B-cell lymphomas mafai ona faʻamaloloina. O togafitiga e mafai ona faifai lemu ai i isi. Afai e leai se faʻailoga o le kanesa pe a maeʻa lau muamua togafitiga, o lona uiga ua e faʻamagaloina. E tatau lava ona e tulitataoina mo ni nai tausaga e mataʻituina mo le toe tupu.

Manatu

O le aofaʻi atoa o le lima-tausaga fua faatatau ola mo non-Hodgkin's lymphoma e 70 pasene. E fesuisuiai tele e tusa ma le ituaiga o B-cell lymphoma ma tulaga i faʻamaoniga. O isi iloiloga o lau matua ma le soifua maloloina atoa.

Mo se faʻataʻitaʻiga, o le DLBCL e mafai ona togafitia i le afa o tagata o loʻo iai. O i latou e amata togafitiga i taimi muamua laasaga e sili atu le lelei o latou manatu nai lo i latou o loʻo mulimuli ane-tulaga faʻamaʻi.

Lau fomaʻi mafai ona avatua ia te oe lau oe lava vavalo faʻavae i luga o lau atoa talaʻaga soifua maloloina.

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