Spironolactone (Aldactone)

Anotusi

• Mo le a
• Faʻafefea ona ave
• 1. Toto maualuga
• 2. Faʻafitauli o le fatu fatu
• 3. ate cirrhosis
• 4. Nephrotic Syndrome
• 5. Edema
• 6. Hypokalemia / hypomagnesaemia
• 7. Togafitiga muamua o le Peraimeri Hyperaldosteronism
• 8. Toto maualuga
• Faiga o gaioiga
• Aafiaga e ono tutupu
• Faʻafitauli

Spironolactone, lauiloa faʻapisinisi o Aldactone, galue o se diuretic, faʻateleina le aveʻesea o le vai e ala i le miaga, ma o se antihypertensive, ma mafai ona faʻaaogaina i le togafitia o le toto maualuga, fulafula e fesoʻotaʻi ma faʻafitauli i le faʻagaioiga o le fatu poʻo faʻamaʻi i le ate ma fatugaʻo, hypokalemia poʻo le togafitia o hyperaldosteronism, mo se faʻataʻitaʻiga.

I nisi tulaga, o lenei fofo mafai ona faatonuina mo le togafitia o fuafua ma ia puipuia le laulu lauulu, peitaʻi o nei talosaga e le o se vaega o le autu faʻailoga mo spironolactone, pe latou te taʻua foi i le afifi faʻaofi.

Spironolactone mafai ona faʻatau i fale talavai, mo le tau e tusa o le 14 i le 45 reais, faʻamoemoe i le filifiliga a le tagata le igoa poʻo le lautele, manaʻomia le faʻaalia o se talavai.

Mo le a

Spironolactone ua faʻailoa mo:

• Toto maualuga;
• Edema mafua mai i le fatu, fatugaʻo poʻo faʻafitauli maʻi;
• Edema Idiopathic;
• Ausilali togafitiga i malignant toto maualuga;
• Hypokalemia pe a fai o isi faiga e manatu e le talafeagai pe le lava foʻi;
• Puipuia ole hypokalemia ma le hypomagnesaemia i tagata o loʻo inu diuretics;
• Suʻesuʻega ma togafitiga o le hyperaldosteronism.

Aʻoaʻo e uiga i isi ituaiga o diuretics ma aʻoaʻo pe faʻafefea ona latou galue.

Faʻafefea ona ave

O le metotia faʻalagolago i le faʻafitauli e tatau ona togafitia:

1. Toto maualuga

O le fualaʻau masani o le 50 mg / aso ile 100 mg / aso, lea ile teteʻe pe ogaoga foʻi mataupu e mafai ona faʻateleina lemu, ile va ole lua vaiaso, e oʻo ile 200 mg / aso. Togafitiga e tatau ona faʻaauau mo le laʻititi ifo o le lua vaiaso e mautinoa ai le lava tali atu i togafitiga. E tatau ona fetuʻunaʻi le inumaga pe a manaʻomia.

2. Faʻafitauli o le fatu fatu

O le fautuaina fautuaina amata i aso uma tui o le 100 mg i se tasi pe vaevaeina fualaʻau, lea e mafai ona fesuiaʻi i le va o le 25 mg ma le 200 mg i aso uma. O le masani masani togafitiga fualaʻau tatau ona fuafuaina mo tagata taʻitasi.

3. ate cirrhosis

Afai o le urinary sodium / urinary potassium ratio e sili atu nai lo le 1, o le masani ai fualaʻa e 100 mg / aso. Afai o lenei faʻatusatusaga e laititi atu i le 1, o le fualaʻau fautuaina o le 200 mg / aso i le 400 mg / aso. O le masani masani togafitiga fualaʻau tatau ona fuafuaina mo tagata taʻitasi.

4. Nephrotic Syndrome

O le fualaʻau masani i tagata matutua o le 100 mg / aso i le 200 mg / aso.

5. Edema

O le fualaʻau masani o le 100 mg i le aso mo tagata matutua ma tusa ma le 3.3 mg ile kilokalama o le mamafa faʻataʻitaʻia i se vaega vaevaeina. O le metotia tatau ona fetuʻunaʻi faʻavae i luga o le tali ma le faʻapalepale o tagata taʻitasi.

6. Hypokalemia / hypomagnesaemia

O se metotia o le 25 mg / aso e oʻo atu i le 100 mg / aso e fautuaina i le togafitia o le hypopotassemia ma / poʻo le hypomagnesemia na faʻaosoina e diuretics, pe a le lava le potasiomi potassium ma / poʻo le magnesium faʻaopoopoga.

7. Togafitiga muamua o le Peraimeri Hyperaldosteronism

A faʻamaonia lelei le faʻamaonia o le hyperaldosteronism e le tele o suʻesuʻega mautinoa, e mafai ona faʻatautaia le spironolactone i tui o le 100 mg i le 400 mg i aso uma e sauniuni ai mo taʻotoga.

8. Toto maualuga

E tatau ona faʻaaoga e fai ma fesoasoani fesoasoani pe a fai e tele le faʻalilolilo o aldosteron, hypokalemia ma metabolic alkalosis. O le fualaʻau amata o le 100 mg / aso, lea e mafai ona faʻateleina, pe a manaʻomia, i vaitaimi o le lua vaiaso, e oʻo atu i le 400 mg / aso.

Faiga o gaioiga

Spironolactone o se faʻapitoa antdistist aldolone, e faʻatinoina tele i luga o le aldolone-faʻalagolago sodium ma potassium ion fesuiaiga nofoaga, o loʻo tu i le mamao faʻataʻoto tubule o le fatugaʻo, e mafua ai le faʻateleina sodium ma vai faʻateʻaina ma faʻateleina potassium taofia.

Aafiaga e ono tutupu

O nisi o aʻafiaga o le spironolactone e ono aofia ai le neoplasm o le fatafata mama, leukopenia, thrombositopenia, faʻaletonu o le electrolyte, suiga i le libido, le mautonu, niniva, faʻafitauli o le manava ma le niniva, le masani ai le galue o le ate, Steve-Johnson syndrome, vailaʻau oona epidermal leiloa, hypertrichosis, mageso, lagomeli, vae vae, tiga ogaoga fatugaʻo, tiga susu, faaletonu masina, gynecomastia ma malaise.

Faʻafitauli

Spironolactone e le tatau ona faʻaaogaina e tagata o loʻo agavaʻa i vaega o le metotia, tagata e ogaoga le faʻamaʻi o le fatugaʻo, faʻaletonu tele o le fatugao gaioiga, anuria, Addison's faʻamaʻi, hyperkalaemia poʻo latou o loʻo faʻaaogaina se vailaʻau eplerenone.