Hemoglobin Electrophoresis

Anotusi

• O le a le hemoglobin electrophoresis?
• O le a le mea e faʻaaoga ai?
• Aisea oute manaʻomia ai le hemoglobin electrophoresis?
• Ole a le mea e tupu ile hemoglobin electrophoresis?
• Mata e tatau ona ou faia se mea e sauniuni ai mo le suʻega?
• E i ai ni lamatiaga i le hemoglobin electrophoresis?
• O le a le uiga o faʻaiuga?
• E iai se isi mea e tatau ona ou iloa e uiga ile hemoglobin electrophoresis?
• Faʻamatalaga

O le a le hemoglobin electrophoresis?

Hemoglobin o se polotini i ou sela mumu toto e ave le okesene mai ou mama i le totoe o lou tino. E tele ituaiga o hemoglobin. Ole hemoglobin electrophoresis ose suʻega e fua ai ituaiga eseese ole hemoglobin ile toto. E vaʻai foʻi mo le masani ai ituaiga o hemoglobin.

Ituaiga masani o hemoglobin aofia ai:

• Hemoglobin (Hgb) A, le ituaiga taatele o hemoglobin i tagata matutua soifua maloloina
• Hemoglobin (Hgb) F, hemoglobin fetal. Lenei ituaiga o hemoglobin e maua i pepe le fananau mai ma pepe faatoa fananau mai. HgbF suia e HgbA e leʻi leva ona fanau mai.

Afai o maualuga o HgbA poʻo HgbF e maualuga pe maualalo tele, e mafai ona faʻailoa mai ai nisi ituaiga o anemia.

E le masani ai ituaiga ole hemoglobin aofia ai:

• Hemoglobin (Hgb) S. Lenei ituaiga o hemoglobin o loʻo maua i selesaito sela faʻamaʻi. O maʻi sela sela o se faʻamaʻi tuufaasolo lea e mafua ai ona faia e le tino ni sela mumu mumu, pei o se selesaito. O sela mumu toto maloloina e mafai ona fetuʻunaʻi ina ia faigofie ai ona latou feoaʻi i ala toto. O sela maʻi e mafai ona mau i totonu o ala o le toto, ma mafua ai tiga matuia ma le tumau, faʻamaʻi, ma isi faʻalavelave.
• Hemoglobin (Hgb) C. O lenei ituaiga hemoglobin e le feaveaʻia lelei le okesene. E mafai ona mafua ai se agamalu ituaiga o anemia.
• Hemoglobin (Hgb) E. Lenei ituaiga o hemoglobin e tele lava maua i tagata o Sautesasae Asia tupuʻaga. Tagata e iai HgbE masani lava leai ni faʻailoga poʻo ni faʻailoga malu ole anemia.

O le suʻesuʻega o le hemoglobin electrophoresis e faʻaogaina ai le eletise i se vaega o le toto. E tuueseese ai le hemoglobin masani ma le masani ai. E mafai ona fua taʻitasi ituaiga o hemoglobin.

Isi igoa: Hb electrophoresis, hemoglobin iloiloga, hemoglobinopathy iloiloina, hemoglobin vaevaeina, Hb ELP, selesaito sela screen

O le a le mea e faʻaaoga ai?

Ole fua ole hemoglobin electrophoresis e fua ai le maualuga ole hemoglobin ma tilotilo ai i ituaiga ole hemoglobin e le masani ai. E masani ona faʻaaogaina e fesoasoani ai ile faʻailoaina ole anemia, maʻi sela sela, ma isi faʻamaʻi ole hemoglobin.

Aisea oute manaʻomia ai le hemoglobin electrophoresis?

Oe ono manaʻomia se faʻataʻitaʻiga pe a fai oe maua faʻailoga o le hemoglobin faʻafitauli. E aofia ai:

• Le lavava
• Paʻu paʻu
• Jaundice, o se tulaga e mafua ai ona lanu samasama lou paʻu ma ou mata
• Tiga ogaoga (maʻi sela sela)
• Faʻafitauli tuputupu aʻe (i tamaiti)

Afai na faʻatoa e maua se pepe, o le a tofotofoina lau pepe fou o se vaega o le siakiina o se pepe fou. Ole faʻamamaina ole pepe faatoa fananau mai ole vaega ole suʻega na ave ile tele o pepe Amerika i se taimi e leʻi leva ona fanau mai. O siaki siaki mo tuʻutuʻuga eseʻese. Ole tele o nei tuutuuga e mafai ona togafitia pe a vave maua.

Atonu e te manaʻo foʻi ile suʻega pe a fai e te ono aʻafia ile maua o se tamaititi e iai le maʻi sela ole selesaito poʻo seisi faʻamaʻi o le hemoglobin. Mea lamatia aofia ai:

• Talafaʻasolopito o aiga
• Talaʻaga aganuʻu
  • I totonu o le Iunaite Setete, o le tele o tagata ma faʻamaʻi sela sela o latou tupuaga Aferika.
  • O le Thalassemia, o le isi foʻi faʻamaʻi o le hemoglobin, e masani ai tagata Italia, Eleni, Sasaʻe o Sasaʻe, Asia i Saute, ma Aferika.

Ole a le mea e tupu ile hemoglobin electrophoresis?

O le polofesa mo le soifua maloloina o le a ave se toto faʻataʻitaʻiga mai se uaua i lou lima, faʻaaoga ai se tamaʻi nila. A maeʻa ona tuʻu i totonu le nila, o le a faʻaputuputuina se vaega laʻititi o le toto i totonu o se faʻamaoniga poʻo se ipu. Atonu e te lagonaina sina tiga pe a alu le nila i totonu pe fafo. Lenei masani ona alu ifo i lalo o le lima minute.

Ina ia faʻataʻitaʻia se pepe fou, o le a faʻamamaina e le tausi soifua maloloina le mulivae o lau pepe i le ava malosi ma tui le mulivae ma se nila laitiiti. O le a tuʻuina mai e le tagata faʻatutu ni nai mataua o le toto ma faʻapipiʻi i luga o le upega tafailagi.

Mata e tatau ona ou faia se mea e sauniuni ai mo le suʻega?

E te le manaʻomia ni sauniuniga faʻapitoa mo se suʻega ole hemoglobin electrophoresis.

E i ai ni lamatiaga i le hemoglobin electrophoresis?

E laʻititi lava le aʻafia ile faia ole suʻega ile toto. E i ai sina tiga poʻo se tiga i le mea na tuu ai le nila, ae o le tele o faʻailoga e vave ona alu ese.

Atonu e lagona e lau pepe sina tamaʻi tipi pe a tui le mulivae, ma ono paʻu le maʻamaʻi i le nofoaga. Lenei e tatau ona vave alu ese.

O le a le uiga o faʻaiuga?

O au faʻaiuga o le a faʻaalia ai ituaiga o hemoglobin o loʻo maua ma tulaga o taʻitasi.

Ole maualuga ole hemoglobin e maualuluga pe maualalo tele atonu ole uiga:

• Thalassemia, o se tulaga e aʻafia ai le gaosia o le hemoglobin. Faʻailoga e amata mai i le agamalu i le ogaoga.
• Uiga o sela feaveaʻi. I le tulaga lea, e tasi le lau selesaito sela sela ma le tasi masani kenera. Ole toʻatele o tagata e leai ni faʻafitauli tau soifua maloloina e maua ai ile sela.
• Maʻi sela sela
• Hemoglobin C faʻamaʻi, o se tulaga e mafua ai le agamalu ituaiga o anemia ma o nisi taimi o le faʻateleina pupula ma soʻoga tiga
• Hemoglobin S-C faamaʻi, o se tulaga e mafua ai le agamalu pe feololo ituaiga o selesaito sela faamaʻi

O au faʻaiuga e ono faʻaalia foi pe o se faʻaletonu e agamalu, agamalu, pe ogaoga foi.

O faʻataʻitaʻiga ole suʻesuʻeina ole hemoglobin e masani ona faʻatusatusa i isi suʻega, e aofia ai le toto atoa ma le toto. A iai ni au fesili e uiga i au iʻuga, talanoa i lau fomaʻi.

Aʻoaʻo atili e uiga i suʻesuʻega falesuesue, vaitau o faʻasino, ma malamalamaaga i iʻuga

E iai se isi mea e tatau ona ou iloa e uiga ile hemoglobin electrophoresis?

A faʻapea e te ono aʻafia ile maua o se tamaititi e maua ile faʻamaʻi ole hemoglobin, atonu e te manaʻo e te talanoa i se faufautua o gafa. O se faufautua kenera o se faʻapitoa aʻoaʻoina faʻapitoa i genetics ma faʻasologa genetic. E mafai ona fesoasoani o ia ia te oe ia malamalama i le maʻi ma le ono ono pasi ia i lau tama.

Faʻamatalaga

1. American Society of Hematology [Initaneti]. Uosigitone D.C .: American Society of Hematology; c2020. Faamai maʻi sela; [taʻua 2020 Jan 10]; [pe tusa ma le 3 pupuni] Avanoa mai: https://www.hematology.org/Patients/Anemia/Sickle-Cell.aspx
2. Cleveland Clinic [Initaneti]. Cleveland (OH): Cleveland Clinic; c2020. Sickle Cell Anemia: Vaaiga aoao; [taʻua 2020 Jan 10]; [pe tusa ma le 3 pupuni] Avanoa mai: https://my.clevelandclinic.org/health/diseases/4579-sickle-cell-anemia
3. Tamaiti Soifua Maloloina mai Nemours [Initaneti]. Jacksonville (FL): Le Nemours Foundation; c1995–2020. Tofotofoga Toto: Hemoglobin Electrophoresis; [taʻua 2020 Jan 10]; [pe tusa ma le 3 pupuni] Avanoa mai: https://kidshealth.org/en/mother/test-electrophoresis.html
4. Lab Tofotofoga lugalaina [Initaneti]. Washington D.C .: American Association mo Vailaʻau Togafitiga; c2001–2020. Hemoglobinopathy Iloiloga; [faʻafouina 2019 Sep 23; taʻua le 2020 Ian 10]; [pe a ma le 2 pupuni] Avanoa mai: https://labtestsonline.org/tests/hemoglobinopathy-evaluation
5. Lab Tofotofoga lugalaina [Initaneti]. Washington D.C .: American Association mo Vailaʻau Togafitiga; c2001–2020. Jaundice; [faʻafouina 2019 Oketopa 30; taʻua le 2020 Ian 10]; [pe a ma le 2 pupuni] Avanoa mai: https://labtestsonline.org/conditions/jaundice
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7. Merck Manual Consumer Version [Initaneti]. Kenilworth (NJ): Merck & Co. Inc. 2020. Hemoglobin C, S-C, ma Faʻamaʻi E; [faafouina 2019 Fep; taʻua le 2020 Ian 10]; [pe a ma le 2 pupuni] Avanoa mai: https://www.merckmanuals.com/home/blood-disorder/anemia/hemoglobin-c,-s-c,-and-e-diseases?query=hemoglobin%20electrophoresis
8. National Heart, Lung, and Blood Institute [Initaneti]. Bethesda (MD): U.S. Matagaluega o le Soifua Maloloina ma Tagata Auaunaga; Tofotofoga Toto; [taʻua 2020 Jan 10]; [pe tusa ma le 3 pupuni] Avanoa mai: https://www.nhlbi.nih.gov/health-topics/blood-tests
9. National Heart, Lung, and Blood Institute [Initaneti]. Bethesda (MD): U.S. Matagaluega o le Soifua Maloloina ma Tagata Auaunaga; Faamai maʻi sela; [taʻua 2020 Jan 10]; [pe tusa ma le 3 pupuni] Avanoa mai: https://www.nhlbi.nih.gov/health-topics/sickle-cell-disease
10. National Heart, Lung, and Blood Institute [Initaneti]. Bethesda (MD): U.S. Matagaluega o le Soifua Maloloina ma Tagata Auaunaga; Thalassemias; [taʻua 2020 Jan 10]; [pe tusa ma le 3 pupuni] Avanoa mai: https://www.nhlbi.nih.gov/health-topics/thalassemias
11. UF Soifua Maloloina: Iunivesite o Florida Soifua Maloloina [Initaneti]. Gainesville (FL): Iunivesite o Florida Soifua Maloloina; c2020. Hemoglobin electrophoresis: Vaaiga aoao; [faafou 2020 Ian 10; taʻua le 2020 Ian 10]; [pe a ma le 2 pupuni] Avanoa mai: https://ufhealth.org/hemoglobin-electrophoresis
12. UW Soifua Maloloina [Initaneti]. Madison (WI): Iunivesite o Wisconsin Falemai ma Falemai Pulega; c2020. Soifua Maloloina Faʻamatalaga: Hemoglobin Electrophoresis: Iʻuga; [faafou 2019 Mar 28; taʻua le 2020 Ian 10]; [pe a ma le 8 pupuni] Avanoa mai: https://www.uwhealth.org/health/topic/medicaltest/hemoglobin-electrophoresis/hw39098.html#hw39128
13. UW Soifua Maloloina [Initaneti]. Madison (WI): Iunivesite o Wisconsin Falemai ma Falemai Pulega; c2020. Soifua Maloloina Faʻamatalaga: Hemoglobin Electrophoresis: Suʻesuʻega Vaaiga Aoao; [faafou 2019 Mar 28; taʻua le 2020 Ian 10]; [pe a ma le 2 pupuni] Avanoa mai: https://www.uwhealth.org/health/topic/medicaltest/hemoglobin-electrophoresis/hw39098.html
14. UW Soifua Maloloina [Initaneti]. Madison (WI): Iunivesite o Wisconsin Falemai ma Falemai Pulega; c2020. Faʻamatalaga o le Soifua Maloloina: Hemoglobin Electrophoresis: O Le a Se Mea e Mafaufau I Ai; [faafou 2019 Mar 28; taʻua le 2020 Ian 10]; [tusa o le 10 pupuni] Avanoa mai: https://www.uwhealth.org/health/topic/medicaltest/hemoglobin-electrophoresis/hw39098.html#hw39144
15. UW Soifua Maloloina [Initaneti]. Madison (WI): Iunivesite o Wisconsin Falemai ma Falemai Pulega; c2020. Faʻamatalaga o le Soifua Maloloina: Hemoglobin Electrophoresis: Aisea E Faia Ai; [faafou 2019 Mar 28; taʻua le 2020 Ian 10]; [pe tusa ma le 3 pupuni] Avanoa mai: https://www.uwhealth.org/health/topic/medicaltest/hemoglobin-electrophoresis/hw39098.html#hw39110

O faʻamatalaga i luga o lenei 'upega tafaʻilagi e le tatau ona faʻaaogaina e fai ma sui o fomaʻi faʻapitoa togafitiga poʻo fautuaga. Faʻafesoʻotaʻi le au tausi soifua pe a iai ni au fesili e uiga i lou soifua maloloina.