Tofotofoga Farmacogenetic

Anotusi

• O le a le faʻataʻitaʻiga o le vailaʻau?
• O le a le mea e faʻaaoga ai?
• Aisea ou te manaʻomia ai le faʻataʻitaʻiga o vailaʻau?
• Ole a le mea e tupu ile taimi ole suʻega ole vailaʻau?
• Mata e tatau ona ou faia se mea e sauniuni ai mo le suʻega?
• E i ai ni lamatiaga i le suʻega?
• O le a le uiga o faʻaiuga?
• E iai se isi mea e tatau ona ou iloa e uiga ile faʻataʻitaʻiga ole vailaʻau?
• Faʻamatalaga

O le a le faʻataʻitaʻiga o le vailaʻau?

Pharmacogenetics, e taʻua foi o le pharmacogenomics, o le suʻesuʻeina lea o le auala e aafia ai le tino i tali a le tino i nisi vailaʻau. O kenera o ni vaega o DNA na faʻasolo mai i lou tina ma lou tama. Latou te aveina faʻamatalaga e iloa ai ou uiga uiga ese, pei o le maualuga ma le lanu o mata. O ou genes e mafai foi ona aʻafia ai le saogalemu ma le aoga o se vailaʻau faʻapitoa mo oe.

O Genes e mafai ona avea ma mafuaʻaga o le tutusa vailaʻau i le tutusa fualaʻau o le a aʻafia ai tagata i ni auala eseʻese. E ono avea foʻi ma mafuaʻaga le mafuaʻaga ole leaga o aʻafiaga o nisi tagata ile vailaʻau, ae o isi e leai.

Vaʻai ile vailaʻau ma vailaʻau e te suʻesuʻe ai ituaiga o vailaʻau ma vailaʻau e ono talafeagai mo oe.

Isi igoa: vailaʻau oona, vailaʻau faʻataʻitaʻi

O le a le mea e faʻaaoga ai?

E mafai ona faʻaaogaina le faʻataʻitaʻiga ole vailaʻau e mafai ai ona:

• Saili pe mafai ona aoga se vailaʻau mo oe
• Saili poʻo le a le sili metotia mafai mo oe
• Valoia pe o le ae maua se itu ogaoga aafiaga mai se vailaʻau

Aisea ou te manaʻomia ai le faʻataʻitaʻiga o vailaʻau?

E mafai e lau tausi soifua maloloina ona faʻatonu nei faʻataʻitaʻiga ae e te leʻi amataina se vailaʻau, pe afai o loʻo e inuina se vailaʻau e leʻo galue ma / pe faʻatupuina ni faʻalavelave leaga.

E naʻo avanoa mo vailaʻau faʻapitoa e avanoa mo suʻesuʻega ole vailaʻau. Lalo o nisi o vailaʻau ma genes e mafai ona tofotofoina. (O igoa o Gene e masani ona ave i mataitusi ma numera.)

Ole a le mea e tupu ile taimi ole suʻega ole vailaʻau?

O suʻega e masani ona faia ile toto poʻo le faua.

Mo se suʻega toto, o se polofesa mo le soifua maloloina o le a ave se toto faʻataʻitaʻiga mai se uaua i lou lima, faʻaaoga ai se tamaʻi nila. A maeʻa ona tuʻu i totonu le nila, o le a faʻaputuputuina se vaega laʻititi o le toto i totonu o se faʻamaoniga poʻo se ipu. Atonu e te lagonaina sina tiga pe a alu le nila i totonu pe fafo. Lenei masani ona alu ifo i lalo o le lima minute.

Mo se faua suʻega, fesili i lau tausi soifua maloloina mo faʻatonuga pe faʻafefea ona avatua lau faʻataʻitaʻiga.

Mata e tatau ona ou faia se mea e sauniuni ai mo le suʻega?

E masani ona e le manaʻomia ni sauniuniga faʻapitoa mo se suʻega ile toto. Afai o faia sau suʻega faua, e le tatau ona 'ai, inu, pe ulaula mo le 30 minute ao le i faia le suʻega.

E i ai ni lamatiaga i le suʻega?

E laʻititi lava le aʻafia ile faia ole suʻega ile toto. E i ai sina tiga poʻo se tiga i le mea na tuu ai le nila, ae o le tele o faʻailoga e vave ona alu ese.

E leai se lamatiaga i le faia o se faua suʻega.

O le a le uiga o faʻaiuga?

Afai na faʻataʻitaʻia oe ae e te leʻi amataina se togafitiga, e mafai e le suʻega ona faʻaalia pe o se vailaʻau e aoga ma / pe afai e te ono aʻafia i ni aʻafiaga matuia. O ni suʻega, e pei o suʻega mo nisi vailaʻau e togafitia ai le maʻilili ma le HIV, e mafai ona faʻaalia ai pe o e ono aʻafia i ni aʻafiaga e lamatia ai le ola. Afai o lea, o le a taumafai lau tautua e suʻe se isi togafitiga.

O faʻataʻitaʻiga e tupu muamua ma aʻo e i ai togafitiga e mafai ona fesoasoani i lau fomaʻi tausi soifua faʻasolosolo le tui talafeagai.

A iai ni au fesili e uiga i au iʻuga, talanoa i lau fomaʻi.

Aʻoaʻo atili e uiga i suʻesuʻega falesuesue, vaitau o faʻasino, ma malamalamaaga i iʻuga

E iai se isi mea e tatau ona ou iloa e uiga ile faʻataʻitaʻiga ole vailaʻau?

O le faʻataʻitaʻiga o le vailaʻau faʻasaienisi e naʻo le faʻaaogaina e iloa ai le tali a se tagata i se vailaʻau faʻapitoa. E le tutusa le mea e pei ole faʻataʻitaʻiga. Ole tele ole suʻesuʻega ole kenera e faʻaogaina e fesoasoani ai ile faʻailoaina o faʻamaʻi pe ono ono aʻafia i faʻamaʻi, faʻailoa se sootaga ile aiga, pe faʻailoa se tasi ile suʻesuʻega solitulafono.

Faʻamatalaga

1. Hefti E, Blanco J. Faʻalauiloaina o le Farmacogenomic Suʻesuʻega ma Nei Faʻasologa o Taualumaga Faʻataʻitaʻiga (CPT), O Se Iloiloga o Taimi ua Tuanaʻi ma Nei. J AHIMA [Initaneti]. 2016 Ian [taʻua 2018 Jun 1]; 87 (1): 56–9. Avanoa mai: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4998735
2. Lab Tofotofoga lugalaina [Initaneti]. Washington D.C: American Association mo vailaʻau Togafitiga; c2001–2018. Faʻataʻitaʻiga o vailaʻau; [faafou 2018 Jun 1; taʻua 2018 Jun 1]; [pe a ma le 2 pupuni] Avanoa mai: https://labtestsonline.org/tests/pharmacogenetic-tests
3. Lab Tofotofoga lugalaina [Initaneti]. Washington D.C: American Association mo vailaʻau Togafitiga; c2001–2018. Le Vateatea o Genetic Testing; [faafou 2017 Nov 6; taʻua 2018 Jun 1]; [pe a ma le 2 pupuni] Avanoa mai: https://labtestsonline.org/articles/genetic-testing?start=4
4. Mayo Clinic: Nofoaga mo Vailaʻau Taʻitoʻatasi [Initaneti]. Mayo Faʻavae mo Aʻoga Faʻafomaʻi ma Suesuega; c1998–2018. Suʻega o Vailaau-Gene; [taʻua 2018 Jun 1]; [pe tusa ma le 3 pupuni] Avanoa mai: http://mayoresearch.mayo.edu/center-for-individualized-medicine/drug-gene-testing.asp
5. Mayo Clinic: Nofoaga mo Vailaʻau Taʻitoʻatasi [Initaneti]. Mayo Faʻavae mo Aʻoga Faʻafomaʻi ma Suesuega; c1998–2018. CYP2D6 / Tamoxifen Pharmacogenomic Lab Tofotofoga; [taʻua 2018 Jun 1]; [pe a ma le 5 pupuni]Avanoa mai: http://mayoresearch.mayo.edu/center-for-individualized-medicine/cyp2d6-tamoxifen.asp
6. Mayo Clinic: Nofoaga mo Vailaʻau Taʻitoʻatasi [Initaneti]. Mayo Faʻavae mo Aʻoga Faʻafomaʻi ma Suesuega; c1998–2018. HLA-B * 1502 / Carbamazepine Pharmacogenomic Lab Tofotofoga; [taʻua 2018 Jun 1]; [tusa o le 4 pupuni] Avanoa mai: http://mayoresearch.mayo.edu/center-for-individualized-medicine/hlab1502-carbamazephine.asp
7. Mayo Clinic: Nofoaga mo Vailaʻau Taʻitoʻatasi [Initaneti]. Mayo Faʻavae mo Aʻoga Faʻafomaʻi ma Suesuega; c1998–2018. HLA-B * 5701 / Abacavir Pharmacogenomic Lab Tofotofoga; [taʻua 2018 Jun 1]; [tusa o le 4 pupuni] Avanoa mai: http://mayoresearch.mayo.edu/center-for-individualised-medicine/hlab5701-abacavir.asp
8. Mayo Clinic: Mayo Medical Laboratories [Initaneti]. Mayo Faʻavae mo Aʻoga Faʻafomaʻi ma Suesuega; c1995–2018. ID faʻataʻitaʻi: PGXFP: Laulaʻiga Faʻapitoa mo Vaʻavaʻaia: Faʻataʻitaʻiga; [taʻua 2018 Jun 1]; [pe tusa ma le 3 pupuni] Avanoa mai: https://www.mayomedicallaboratories.com/test-catalog/Specimen/65566
9. National Cancer Institute [Initaneti]. Bethesda (MD): U.S. Matagaluega o le Soifua Maloloina ma Tagata Auaunaga; NCI Lomifefiloi o Kanesa Aiaiga: gafa; [taʻua 2018 Jun 1]; [pe tusa ma le 3 pupuni] Avanoa mai: https://www.cancer.gov/publications/dictionaries/cancer-terms/search?contains=false&q;=gene
10. National Heart, Lung, and Blood Institute [Initaneti]. Bethesda (MD): U.S. Matagaluega o le Soifua Maloloina ma Tagata Auaunaga; Tofotofoga Toto; [taʻua 2018 Jun 1]; [pe tusa ma le 3 pupuni] Avanoa mai: https://www.nhlbi.nih.gov/health-topics/blood-tests
11. NIH National Institute of General Medical Saienisi [Initaneti]. Bethesda (MD): U.S. Matagaluega o le Soifua Maloloina ma Tagata Auaunaga; Pharmacogenomics; [faafou 2017 Oketopa; taʻua 2018 Jun 1]; [tusa o le 4 pupuni] Avanoa mai: https://www.nigms.nih.gov/education/Pages/factsheet-pharmacogenomics.aspx
12. NIH U.S. National Library of Medicine: Genetics Home Reference [Initaneti]. Bethesda (MD): U.S. Matagaluega o le Soifua Maloloina ma Tagata Auaunaga; O le a le vailaʻau oona?; 2018 Me 29 [taʻua 2018 Jun 1]; [tusa o le 4 pupuni] Avanoa mai: https://ghr.nlm.nih.gov/primer/genomicresearch/pharmacogenomics
13. UF Soifua Maloloina: Iunivesite o Florida Soifua Maloloina [Initaneti]. Iunivesite o Florida; c2018. Faʻafefea e au genes ona faʻatosina vailaʻau talafeagai mo oe; 2016 Ian 11 [toefaʻaleleia 2018 Jun 1; taʻua 2018 Jun 1]; [pe a ma le 2 pupuni] Avanoa mai: https://ufhealth.org/blog/how-your-genes-influence-what-medicines-are- Right-you
14. UW Health American Family Children's Hospital [Initaneti]. Madison (WI): Iunivesite o Wisconsin Falemai ma Falemai Pulega; c2018. Tamaiti Soifua Maloloina: Pharmacogenomics; [taʻua 2018 Jun 1]; [tusa o le 4 pupuni] Avanoa mai: https://www.uwhealthkids.org/kidshealth/en/mother/pharmacogenomics.html/

O faʻamatalaga i luga o lenei 'upega tafaʻilagi e le tatau ona faʻaaogaina e fai ma sui o fomaʻi faʻapitoa togafitiga poʻo fautuaga. Faʻafesoʻotaʻi le au tausi soifua pe a iai ni au fesili e uiga i lou soifua maloloina.